Deep vein thrombosis in a woman taking oral combined contraceptive pills
Kiran G. Piparva1★, Jatin G. Buch1★ Corresponding author
- 1Department of Pharmacology, P.D.U. Medical College, Rajkot, Gujarat, India.
CORRESPONDENCE
Kiran G. Piparva
Department of Pharmacology, P.D.U. Medical College, Rajkot, Gujarat, India.
Volume 2, Issue 3 · pp. 185–6 · PUBLISHED 2011 · DOI: 10.4103/0976-500X.83284
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ABSTRACT
Oral combined contraceptive pill (OCCP) is popular as birth control pills. Like all other drugs, they are not free from risks. Women taking certain types of OCCP have higher risk of developing deep vein thrombosis (DVT). A 29 year old married woman had taken OCCP for 3.5 months, developed deep vein thrombosis of left leg. Hereditary and acquired causes of DVT were excluded. She was treated with parenteral and oral anticoagulants simultaneously and was advised to discontinue OCCP. Initially the risk of blood clot was believed to be due to dose of estrogen but recent study relates it to the type of progesterone involved in OCCP. Thus, it is still a matter of debate, whether to associate risk of DVT to the amount of estrogen alone or also to the type of progestin. Apart from careful selection of patients, one should also look for the risk of venous thromboembolism irrespective of type of OCCP prescribed.
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Piparva, K. G., & Buch, J. G. (2011). Deep vein thrombosis in a woman taking oral combined contraceptive pills. Journal of Pharmacology and Pharmacotherapeutics, 2(3), 185–6. https://doi.org/10.4103/0976-500X.83284