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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Effect of Erythrina variegata on experimental atherosclerosis in guinea pigs

    Mangathayaru Kalachaveedu1★, Sarah Kuruvilla2, K. Balakrishna3★ Corresponding author

    1. 1Faculty of Pharmacy, India.
    2. 2Department of Pathology, Sri Ramachandra University, Porur, India.
    3. 3Department of Chemistry, Captain Srinivasamurty Drug Research Institute for Ayurveda and Siddha, Arumbakkam, Chennai - 600 116, India.

    CORRESPONDENCE

    Mangathayaru Kalachaveedu

    Faculty of Pharmacy, India.

    kvmanga@yahoo.com

    Volume 2, Issue 4 · pp. 285–287 · PUBLISHED 2011 · DOI: 10.4103/0976-500X.85949

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Leaves of Erythrina variegata (Indian coral tree) (family: Fabaceae) eaten as a pot herb, are used as an antiobesity drug in Siddha medicine.[1] It has folkloric reputation as antiinflammatory in India, China and South East Asia, and different parts of the plant are reported with insecticidal, hemagglutinating, curaric, skeletal muscle relaxant, feeding deterrent, antispasmodic, antimycobacterial and antiosteoporotic activities.[2] In this study, the infl uence of the total alcohol extract of E. variegata (Ev) on experimental atherosclerosis in guinea pigs has been evaluated (IAEC approved, Ref: IAEC/SRMC and RI/41/2005). The extract was well tolerated, with no signs of toxicity up to 2 g/kg b.wt. in the acute toxicity study.

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      Kalachaveedu, M., Kuruvilla, S., & Balakrishna, K. (2011). Effect of Erythrina variegata on experimental atherosclerosis in guinea pigs. Journal of Pharmacology and Pharmacotherapeutics, 2(4), 285–287. https://doi.org/10.4103/0976-500X.85949