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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Carbamazepine‑induced hypertension: A rare case

    Preeti Kharb1★, Niti Mittal1, Mahesh C. Gupta1★ Corresponding author

    1. 1Department of Pharmacology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India.

    CORRESPONDENCE

    Preeti Kharb

    Department of Pharmacology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India.

    Received: 25-10-2014; Revised: 17-12-2014; Accepted: 02-08-2015.

    Volume 6, Issue 4 · pp. 216–218 · PUBLISHED 2015 · DOI: 10.4103/0976-500X.171879

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    A 74‑year‑old female with trigeminal neuralgia developed hypertension after the initiation of carbamazepine therapy. The time sequence of start of the suspected drug and onset of hypertension are consistent with the diagnosis. The hypertension did not resolve with antihypertensive therapy or dose reduction of carbamazepine. Patient recovered after the carbamazepine therapy was discontinued. The positive rechallenge and positive dechallenge showed association of carbamazepine therapy with hypertension as its adverse effect. This is a rare case that we report of carbamazepine‑induced hypertension and this report may act as alerting mechanism to the health care professionals especially neurologists.

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      Kharb, P., Mittal, N., & Gupta, M. C. (2015). Carbamazepine‑induced hypertension: A rare case. Journal of Pharmacology and Pharmacotherapeutics, 6(4), 216–218. https://doi.org/10.4103/0976-500X.171879