Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
Vinayaka Anuhya1, Sushil Kiran Kunder1, Sharath Madhyastha1★, Veena Nayak1, Raviraja V. Acharya1, Kusugodlu Ramamoorthi1, Avinash Arivazhahan1, Rahul Sai Gangula1★ Corresponding author
- 1Departments of Pharmacology and Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
CORRESPONDENCE
Sharath Madhyastha
Departments of Pharmacology and Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Received: 01-05-2017; Revised: 29-06-2017; Accepted: 09-08-2017.
Volume 8, Issue 3 · pp. 145–147 · PUBLISHED 2017 · DOI: 10.4103/jpp.JPP_64_17
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ABSTRACT
Cephalosporins are a commonly used class of antibiotics in various types of infections. Cefepime, a fourth-generation cephalosporin, has been reported to cause neurotoxicity, which can present itself as varied manifestations. Nonconvulsive status epilepticus (NCSE) is a rare manifestation of this neurotoxicity. This condition often proves difficult to diagnose because it is chiefly an electroencephalogram-based diagnosis. The authors report a case of cefepime-induced NCSE in a 57-year-old female patient with compromised renal status.
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Anuhya, V., Kunder, S. K., Madhyastha, S., Nayak, V., Acharya, R. V., Ramamoorthi, K., Arivazhahan, A., & Gangula, R. S. (2017). Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus. Journal of Pharmacology and Pharmacotherapeutics, 8(3), 145–147. https://doi.org/10.4103/jpp.JPP_64_17