Levosulpiride-induced Movement Disorders
Supriyo Choudhury1, Koustav Chatterjee2, Ravi Singh2, Shantanu Shubham2, Santosh Trivedi2, Suparna Chatterjee2, Hrishikesh Kumar2★★ Corresponding author
- 1Department of Neurology, RGC Research Centre, Institute of Neurosciences, Kolkata, West Bengal, India.
- 2Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
CORRESPONDENCE
Hrishikesh Kumar
Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Received: 02-03-2017; Revised: 13-05-2017; Accepted: 10-07-2017.
Volume 8, Issue 4 · pp. 177–81 · PUBLISHED 2017 · DOI: 10.4103/jpp.JPP_32_17
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ABSTRACT
We reported a series of patients who presented with LSP-induced movement disorders specifically, dyskinetic movements. We have presented one case of LSP-induced parkinsonism and summarized ten cases of LSP-induced dyskinesia. The causality of the adverse drug reaction was assessed systematically using a validated rating system, and we extensively qualified the clinical presentation of each case of dyskinesia using a clinical rating scale. We described an unusual case of acute onset LSP-induced parkinsonism in a 56-year-aged female. The mean age of ten patients of LSP-induced dyskinesia was 65.3 years (standard deviation 10.4), and 25% of patients were female. They were consuming suspected medication for a median duration of 13 months (range 1–60 months). We noted LSP-induced dyskinesia was challenging to treat as its resolution is often incomplete even with adequate treatment.
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Choudhury, S., Chatterjee, K., Singh, R., Shubham, S., Trivedi, S., Chatterjee, S., & Kumar, H. (2017). Levosulpiride-induced Movement Disorders. Journal of Pharmacology and Pharmacotherapeutics, 8(4), 177–81. https://doi.org/10.4103/jpp.JPP_32_17