Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis Essential Oils Inhibit the Growth of Some Bacterial Triggers of Inflammatory Diseases
Célia Barillot1,2, Ian Edwin Cock1,3★★ Corresponding author
- 1Environmental Futures Research Institute, Griffith University, Brisbane, AUSTRALIA..
- 2School of Biology, Ecole de Biologie Industrielle (EBI), Cergy, FRANCE..
- 3School of Environment and Science, Griffith University, Brisbane, AUSTRALIA..
CORRESPONDENCE
Ian Edwin Cock
Environmental Futures Research Institute, Griffith University, Brisbane, AUSTRALIA..
Volume 11, Issue 2 · pp. 81–87 · PUBLISHED · DOI: 10.5530/pc.2021.2.17
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ABSTRACT
Introduction:Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis are endemic Australian plants. Decoctions, infusions and essential oils produced from the leaves were used traditionally to treat a variety of bacterial diseases. Despite this, these species have not been rigorously examined for antibacterial properties against many pathogens. Methods:The antimicrobial activity of K. ambigua and K. f lavescens essential oils and a K. ambigua hydrosol was investigated by disc diffusion and liquid dilution MIC assays against a panel of pathogenic bacteria. Toxicity was determined using the Artemia franciscana nauplii bioassay. Results: K. ambigua and K. flavescens essential oils displayed noteworthy growth inhibitory activity against A. baylyi, K. pneumonia, P. mirabilis and P. aeruginosa (MIC values substantially <1000μg/mL). Indeed, MIC values as low as 33μg/mL were noted against P. aeruginosa. Noteworthy growth inhibitory activity was also noted for the K. ambigua hydrosol against A. baylyi and P. aeruginosa. All extracts were determined to be non-toxic in the Artemia franciscana nauplii bioassay, indicating their safety for internal use as well as for topical uses. Conclusion: The lack of toxicity of the Kunzea spp. extracts and their growth inhibitory bioactivity against a panel of pathogenic bacteria partially validate the traditional usage of these species to treat bacterial diseases and indicate their potential in the development of antiseptic agents.
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Barillot, C., & Cock, I. E. (). Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis Essential Oils Inhibit the Growth of Some Bacterial Triggers of Inflammatory Diseases. Pharmacognosy Communications, 11(2), 81–87. https://doi.org/10.5530/pc.2021.2.17