Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Pharmacognosy CommunicationsNOW IN
    Article

    Mirbelia oxylobioides F. Muell. Leaf Extracts Lack Antibacterial Activity and are Non-toxic in vitro

    Ian Edwin Cock1,2★★ Corresponding author

    1. 1Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA..
    2. 2School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA..

    CORRESPONDENCE

    Ian Edwin Cock

    Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA..

    i.cock@griffith.edu.au

    Volume 11, Issue 2 · pp. 95–99 · PUBLISHED · DOI: 10.5530/pc.2021.2.19

    View on Pharmacogn. Commn. original site ↗

    ABSTRACT

    Introduction:The development of bacterial strains that are resistant to multiple antibiotics has made the discovery of new antibiotics a priority for medical research. Examination of plants for new antimicrobial agents is an attractive prospect and numerous recent studies have screened plants for antibacterial activity. Despite this, Australian native plants have been relatively neglected. Mirbelia oxylobioides F. Muell. is a native Australian shrub of the family Fabaceae. Very few studies have yet examined species for antibacterial properties against human pathogens. Methods:The ability of M. oxyloboides leaf extracts to inhibit the growth of a panel of bacterial pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana nauplii bioassay. Results: M. oxyloboides methanolic and aqueous extracts were ineffective at inhibiting the growth of gram-positive and gram-negative panels of bacteria. The extracts were non-toxic or of low toxicity following 24 h exposure. Conclusion:The M. oxyloboides leaf extracts lacked growth inhibitory bioactivity against a panel of pathogenic bacteria and were non-toxic in the Artemia nauplii assay. However, these extracts may have other therapeutic properties and testing against protozoa, fungi, virus and tumour cells is required.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Cock, I. E. (). Mirbelia oxylobioides F. Muell. Leaf Extracts Lack Antibacterial Activity and are Non-toxic in vitro. Pharmacognosy Communications, 11(2), 95–99. https://doi.org/10.5530/pc.2021.2.19