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    Pharmacognosy CommunicationsNOW IN
    Article

    Rosella (Hibiscus sabdariffa L.) Tea may Protect against Alzheimer’s Disease

    Ian E Cock1,2★★ Corresponding author

    1. 1School of Environment and Science, Nathan Campus, Griffith University, Brisbane, Queensland, AUSTRALIA..
    2. 2Centre for Planetary Health and Food Security, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA..

    CORRESPONDENCE

    Ian E Cock

    Centre for Planetary Health and Food Security, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA..

    i.cock@griffith.edu.au

    Volume 13, Issue 1 · pp. 45 · PUBLISHED · DOI: 10.5530/pc.2023.1.7

    View on Pharmacogn. Commn. original site ↗

    ABSTRACT

    A recent study from a Pohang University, Korea group has reported that the hydroflavone gossypeptin, which is found in relative abundance in Hibiscus sabdariffa L., has therapeutic effects in a 5XFAD Alzheimer’s Disease (AD) mouse model.1 That mouse strain possesses human APP and PSEN1 transgenes, which are linked to familial AD and are known to enhance β-amyloid protein accumulation in brain cells. Mice treated with gossypeptin displayed significantly decreased cognitive impairment similar to those caused by AD.

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        Cock, I. E. (). Rosella (Hibiscus sabdariffa L.) Tea may Protect against Alzheimer’s Disease. Pharmacognosy Communications, 13(1), 45. https://doi.org/10.5530/pc.2023.1.7