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    Pharmacognosy CommunicationsNOW IN
    Article

    Phragmites australis (Cav.) Trin. Ex Steud. Leaf Extracts Lack Anti-bacterial Activity and are Non-toxic in vitro

    Getmore Rumbudzai Chikowe1, Lindiwe Nomathemba Mpala1, Ian Edwin Cock1,2★★ Corresponding author

    1. 1School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA..
    2. 2Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA..

    CORRESPONDENCE

    Ian Edwin Cock

    School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA..

    I.Cock@griffith.edu.au

    Received: 10-08-2023; Revised: 26-08-2023; Accepted: 20-09-2023.

    Volume 13, Issue 4 · pp. 169–175 · PUBLISHED · DOI: 10.5530/pc.2023.4.27

    View on Pharmacogn. Commn. original site ↗

    ABSTRACT

    Introduction:The recent development of extensively antibiotic resistant bacteria has necessitated the search for novel anti-bacterial compounds. An examination of aromatic plants and traditional medicines is an attractive option for drug discovery. Phragmites australis (Cav.) Trin. Ex Steud. Reed is native to many regions globally, including Australia. It has yet to be tested for antibacterial activity. Materials and Methods:The ability of P. australis leaf extracts to inhibit the growth of a panel of bacterial pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana nauplii bioassay. Results:P. australis leaf methanolic and aqueous extracts were completely ineffective at inhibiting the growth of gram-positive and gram-negative panels of bacteria. The extracts were nontoxic in the Artemia nauplii bioassay following 24 hr exposure. Conclusion: P. australis leaf extracts were completely ineffective bacterial growth inhibitors. However, these extracts may have other therapeutic properties and testing against protozoa, virus and tumour cells is required.

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      Chikowe, G. R., Mpala, L. N., & Cock, I. E. (). Phragmites australis (Cav.) Trin. Ex Steud. Leaf Extracts Lack Anti-bacterial Activity and are Non-toxic in vitro. Pharmacognosy Communications, 13(4), 169–175. https://doi.org/10.5530/pc.2023.4.27