Volume 10, Issue 1

Original Article

1. Article

   Evaluation of Protective Effect of Glycyrrhiza glabra L. Extract on Isoniazid-Rifampicin Induced Hepatocellular Damage in Rats

   Chanchala Haldkar, Anupam Jaiswal, Aditya Ganeshpurkar, Nazneen Dubey

   pp. 18–22 · DOI: 10.5530/pc.2020.1.4 · Published

   Context: Haphazard use of drugs is one of the key reasons for progression of liver diseases. Drugs such as paracetamol, isoniazid, rifampicin etc. cause hepatotoxicity. There is currently no single synthetic drug which i…

2. Article

   In vitro Antiplasmodial and Cytotoxic activity of Three Medicinal Plants used Traditionally for Treatment of Malaria

   Ruth Anyango Omole, Mainen Julius Moshi, Muhammad Ilias, Walker Larry, Hamisi M. Malebo, Leonida Kerubo Omosa, Jacob O. Midiwo

   pp. 2–6 · DOI: 10.5530/pc.2020.1.2 · Published

   Introduction: Reports of emergence of Artemisinin Combination Therapies (ACTs) resistant malaria parasites in Greater Mekong region and Equatorial Guinea, is a strong reason necessitating increased efforts to discover ne…

3. Article

   Eucalyptus grandis W. Hill ex Maiden Leaf and Flower Extracts Lack Antibacterial activity and are Non-toxic in vitro

   Getmore Chikowe, Lindiwe Mpala, Ian Edwin Cock

   pp. 23–29 · DOI: 10.5530/pc.2020.1.5 · Published

   Introduction: Closely related plant species often share similar secondary metabolites and bioactivities and are therefore good targets for bioactivity testing when one or more species within a genus are known to possess …

4. Article

   The Inhibitory Activity of Banksia collina R.Br. and Banksia oblongifolia Cav. Methanolic Leaf Extracts against a Panel of Bacterial Pathogens

   Ian Edwin Cock

   pp. 30–36 · DOI: 10.5530/pc.2020.1.6 · Published

   Introduction: The development of multi-antibiotic resistant strains of bacteria has necessitated the search for new, effective antibacterial therapies. B. collina and B. oblongifolia leaves were used by Australian Aborig…

5. Article

   Brachychiton acerifolius (A.Cunn. ex G.Don) Macarthur and C. moore Leaf and Flower Extracts Inhibit the Growth of a Panel of Pathogenic Bacteria

   Ian Edwin Cock

   pp. 37–43 · DOI: 10.5530/pc.2020.1.7 · Published

   Introduction: Brachychiton acerifolius (A.Cunn. ex G.Don) Macarthur and C. moore is a large tree that is native to subtropical regions of the east of Australia. Decoctions and infusions produced from the leaves of the re…

6. Article

   Antiproliferative Activity of Secondary Metabolites from Zanthoxylum zanthoxyloides Lam: In vitro and in silico Studies

   Moses Andima, Paolo Coghi, Li Jun Yang, Vincent Kam Wai Wong, Chrispus Mutuku Ngule, Matthias Heydenreich, Albert Jairo Ndakala, Abiy Yenesew, Solomon Derese

   pp. 44–51 · DOI: 10.5530/pc.2020.1.8 · Published

   Background: Plant derived compounds have provided proming leads in search for safer anticancer chemotherapies. Zanthoxylum zanthoxyloides is a common medicinal plant in Uganda whose bioactive composition has not been ful…

7. Article

   Ficus racemosa L. Leaf Extracts Lack Antibacterial activity and are Toxic in vitro

   Lindiwe Mpala, Getmore Chikowe, Ian Edwin Cock

   pp. 52–56 · DOI: 10.5530/pc.2020.1.9 · Published

   Introduction: Closely related plant species often share similar secondary metabolites and bioactivities and are therefore good targets for bioactivity testing when one or more species within a genus are known to possess …

8. Article

   Climate Change, Acupuncture and Traditional Chinese Herbal Medicines

   Mohamad Hesam Shahrajabian, Wenli Sun, Qi Cheng

   pp. 57–59 · DOI: 10.5530/pc.2020.1.10 · Published

   Introduction: China is the vast country which has the highest population and providing enough and stable food is a challenge in China, and climate change is expected to exacerbate problems. Methods: Literature search was…

9. Article

   Rosa canina L. Fruit Extracts Inhibit the Growth of Bacterial Triggers of some Autoimmune Inflammatory Diseases and Potentiate the activity of Conventional Antibiotics

   Yujun Wang, Yushu Liang, Ian Edwin Cock

   pp. 7–17 · DOI: 10.5530/pc.2020.1.3 · Published

   Introduction: An increase in antibiotic resistance and a corresponding decrease in antimicrobial discovery have directed researchers towards alternative therapies, including plant based medicines. However, synergistic co…