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    A Review on the Pharmacological Activities and Phytochemicals of Alpinia officinarum (Galangal) Extracts Derived from Bioassay‑Guided Fractionation and Isolation

    Aida Maryam Basri1, Hussein Taha2, Norhayati Ahmad2★★ Corresponding author

    1. 1Herbal Drug Discovery Laboratory, BRUNEI DARUSSALAM.
    2. 2Environmental and Life Sciences, Faculty of Science, Universiti Brunei Darussalam, Gadong BE1410, BRUNEI DARUSSALAM.

    CORRESPONDENCE

    Norhayati Ahmad

    Environmental and Life Sciences, Faculty of Science, Universiti Brunei Darussalam, Gadong BE1410, BRUNEI DARUSSALAM.

    norhayati.ahmad@ubd.edu.bn

    Volume 11, Issue 21 · pp. 43–56 · PUBLISHED · DOI: 10.4103/phrev.phrev_55_16

    View on Pharmacogn. Rev. original site ↗

    ABSTRACT

    The rhizomes of Alpinia officinarum Hance have been used conventionally for the treatment of various ailments, triggering a wide interest from the scientific research community on this ethnomedicinal plant. This review summarizes the phytochemical and pharmacological properties of the extracts and fractions from A. officinarum, a plant species of the Zingiberaceae family. Different parts of the plant – leaves, roots, rhizomes, and aerial parts – have been extracted in various solvents – methanol, ethanol, ethyl acetate, hexane, dichloromethane, aqueous, chloroform, and petroleum ether, using various techniques – Soxhlet extraction, maceration, ultrasonication, and soaking, whereas fractionation of the plant extracts involves the solvent–solvent partition method. The extracts, fractions, and isolated compounds have been studied for their biological activities – antioxidant, antibacterial, anti‑inflammatory, anticancer, antiproliferative, inhibition of enzymes, as well as the inhibition of nitric oxide production. More findings on A. officinarum are certainly important to further develop potential bioactive drug compounds.

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      Basri, A. M., Taha, H., & Ahmad, N. (). A Review on the Pharmacological Activities and Phytochemicals of Alpinia officinarum (Galangal) Extracts Derived from Bioassay‑Guided Fractionation and Isolation. Pharmacognosy Reviews, 11(21), 43–56. https://doi.org/10.4103/phrev.phrev_55_16