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    Euterpe oleraceae (Açaí), Bixa orellana (Annatto), and Myrciaria dubia (Camu-camu): A Review of Preclinical Evidence of Anti-senescence Potential

    Ester Lopes de Melo1, Arlindo César Matias Pereira2, Aline Lopes do Nascimento3, José Carlos Tavares Carvalho1,3★★ Corresponding author

    1. 1Department of Biological and Health Sciences, Postgraduate Program in Tropical Biodiversity, Federal University of Amapá, Rodovia Juscelino Kubitschek, km 02, Macapá CEP 68903-419, Amapá, BRAZIL.
    2. 2Department of Pharmaceutical Sciences, Pharmaceutical Sciences Faculty of Ribeirão Preto, University of São Paulo, São Paulo, BRAZIL.
    3. 3Department of Biological and Health Sciences, Pharmaceutical Innovation Program, Universidade Federal do Amapá, Rodovia Juscelino Kubitschek, km 02, Macapá CEP 68903-419, Amapá, BRAZIL.

    CORRESPONDENCE

    José Carlos Tavares Carvalho

    Department of Biological and Health Sciences, Postgraduate Program in Tropical Biodiversity, Federal University of Amapá, Rodovia Juscelino Kubitschek, km 02, Macapá CEP 68903-419, Amapá, BRAZIL.

    farmacos@unifap.br

    Received: 25-06-2023; Revised: 27-09-2023; Accepted: 17-10-2023.

    Volume 17, Issue 34 · pp. 406–417 · PUBLISHED · DOI: 10.5530/phrev.2023.17.16

    View on Pharmacogn. Rev. original site ↗

    ABSTRACT

    Aging is a complex process resulting from internal and external changes, culminating in a decreased efficacy of cognitive and other biological functions. Studies report that oxidative stress, immunosenescence, inflammaging, and cell senescence are involved in aging. Continuous research is performed seeking treatments delaying such processes to achieve healthy aging, including nutrition and nutraceuticals. In this article, we review the potential of some plants from the Amazon rainforest that have been gaining attention in healthspan, namely Euterpe oleraceae (Açaí), Myrciaria dubia (Camu-camu), and Bixa orellana (Annatto).

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      Melo, E. L. D., Pereira, A. C. M., Nascimento, A. L. D., & Carvalho, J. C. T. (). Euterpe oleraceae (Açaí), Bixa orellana (Annatto), and Myrciaria dubia (Camu-camu): A Review of Preclinical Evidence of Anti-senescence Potential. Pharmacognosy Reviews, 17(34), 406–417. https://doi.org/10.5530/phrev.2023.17.16