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    A Systematic Review on Phytochemistry and Pharmacological Activity of the Plant Hymenocallis littoralis (Jacq.) Salisb

    Saurav Talukdar1, Suman Kumar2★, Sarbanga Bezbaruah1, Prerana Kashyap1, Mohsin Ahmed1, Rupjyoti Majumder1, Rajsekhar Das1, N. Anirudh Singh3★ Corresponding author

    1. 1Royal School of Pharmacy, The Assam Royal Global University, Betkuchi Guwahati, Assam, INDIA.
    2. 2Department of Pharmaceutical Science, Rabindranath Thakur Vishwavidyalaya, Hojai, Assam, INDIA.
    3. 3Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati, Assam, INDIA.

    CORRESPONDENCE

    Suman Kumar

    Department of Pharmaceutical Science, Rabindranath Thakur Vishwavidyalaya, Hojai, Assam, INDIA.

    smnkmr33@gmail.com

    Received: 16-12-2025; Revised: 06-01-2026; Accepted: 23-02-2026.

    Volume 20, Issue 39 · pp. 63–78 · PUBLISHED · DOI: 10.5530/phrev.20260044

    View on Pharmacogn. Rev. original site ↗

    ABSTRACT

    Hymenocallis littoralis (Jacq.) Salisb., commonly known as the Beach spider lily is a perennial herbaceous plant that belongs to the family Amaryllidaceae; well known for its distinctive ethnomedicinal uses against different serious ailments. The review critically analysed the distribution, traditional uses, phytoconstituents, and pharmacological activity of the plant H. littoralis. All the information described in this study was collected by using the electronic databases comprising PubMed and Google Scholar using the general search terms “Hymenocallis littoralis”, “traditional uses”, “phytochemical”, and “pharmacological activity”. The outcome of the study reveals that different parts of the plant, such as the bulb, root, stem, leaves, and flower, contain a wide variety of phytoconstituents, including alkaloids, flavonoids, phenolics, and volatile oils. To date, more than 30 alkaloids have been isolated from different parts of the plant. Among them, pancratistatin and lycorine are most commonly present, exhibiting diverse pharmacological activities. Similarly, other secondary metabolites such as phenolics and volatile oils are also isolated and reported in various scientific literature. The plant has also been reported for its significant traditional use by various indigenous communities in China, Mexico, Central America, and the Philippines for the management of wound healing, rheumatic joint pain, inflammation and pain, hemorrhoids, freckles, and blemishes. The pharmacological activity reveals that the plant shows potential anti-microbial, anthelmintic, anti-fungal, anti-cancer, anti-viral, and wound healing activity in variousin vitro as well as in vivo. The study provides comprehensive and updated information regarding the plant profile and advocates the need for a clinical trial to find out unexplored lead molecules for drug discovery.

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      Talukdar, S., Kumar, S., Bezbaruah, S., Kashyap, P., Ahmed, M., Majumder, R., Das, R., & Singh, N. A. (). A Systematic Review on Phytochemistry and Pharmacological Activity of the Plant Hymenocallis littoralis (Jacq.) Salisb. Pharmacognosy Reviews, 20(39), 63–78. https://doi.org/10.5530/phrev.20260044