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    Interkingdom Three-Way Synergy Modulating Adaptation and Secondary Metabolites

    Vikrant Arya1, Ranjeet Kaur Parmar2 Corresponding author

    1. 1Department of Pharmaceutical Sciences, Government Pharmacy College Rakkar, Kangra, Himachal Pradesh, INDIA.
    2. 2Department of Pharmaceutical Sciences, Government Pharmacy College Kangra at Nagrota Bagwan, Himachal Pradesh, INDIA.

    CORRESPONDENCE

    Vikrant Arya

    Department of Pharmaceutical Sciences, Government Pharmacy College Rakkar, Kangra, Himachal Pradesh, INDIA.

    arya.vikrant30@gmail.com

    Received: 02-11-2025; Revised: 29-12-2025; Accepted: 12-02-2026.

    Volume 20, Issue 39 · pp. 98–101 · PUBLISHED · DOI: 10.5530/phrev.20260041

    View on Pharmacogn. Rev. original site ↗

    ABSTRACT

    Mutualistic complexities in nature represent an inherent part of adaptation. Interkingdom interactions among organisms helped them to survive against biotic and abiotic stress. Although mutualistic associations have been commonly observed among plants-fungi and plant-virus but the concept of tripartite association involving plants-fungus-virus has not been explored so far. The literature review depicted the presence of interactions between plants and the fungus, in which fungal endophytes/AMF aid in plant adaptation. In the case of plant-virus interactions, several viruses aid in modulating the secondary metabolites. The associated mutualistic interactions among organisms complement their survival in nature.

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      Arya, V., & Parmar, R. K. (). Interkingdom Three-Way Synergy Modulating Adaptation and Secondary Metabolites. Pharmacognosy Reviews, 20(39), 98–101. https://doi.org/10.5530/phrev.20260041