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    Phytochemistry and medicinal properties of Phaleria macrocarpa (Scheff.) Boerl. extracts

    Rabia Altaf1★, Mohammad Zaini Bin Asmawi1, Aidiahmad Dewa2, Amirin Sadikun3, Muhammad Ihtisham Umar1★ Corresponding author

    1. 1Departments of Pharmacology, School of Pharmaceutical Sciences, University Sains Malaysia, Minden, Pulau Pinang, MALAYSIA.
    2. 2Physiology, School of Pharmaceutical Sciences, University Sains Malaysia, Minden, Pulau Pinang, MALAYSIA.
    3. 3Pharmaceutical Chemistry, School of Pharmaceutical Sciences, University Sains Malaysia, Minden, Pulau Pinang, MALAYSIA.

    CORRESPONDENCE

    Rabia Altaf

    Departments of Pharmacology, School of Pharmaceutical Sciences, University Sains Malaysia, Minden, Pulau Pinang, MALAYSIA.

    rabia.ihtisham@gmail.com

    Received: 05-12-2012; Revised: 03-02-2013; Accepted: 06-05-2013.

    Volume 7, Issue 13 · pp. 73–80 · PUBLISHED 1 June 2013 · DOI: 10.4103/0973-7847.112853

    View on Pharmacogn. Rev. original site ↗

    ABSTRACT

    Phaleria macrocarpa, commonly known as Mahkota dewa is a medicinal plant that is indigenous to Indonesia and Malaysia. Extracts of P. macrocarpa have been used since years in traditional medicine that are evaluated scientifically as well. The extracts are reported for a number of valuable medicinal properties such as anti‑cancer, anti‑diabetic, anti‑hyperlipidemic, anti‑inflammatory, anti‑bacterial, anti‑fungal, anti‑oxidant and vasorelaxant effect. The constituents isolated from different parts of P. macrocarpa include Phalerin, gallic acid, Icaricide C, magniferin, mahkoside A, dodecanoic acid, palmitic acid, des‑acetylflavicordin‑A, flavicordin‑A, flavicordin‑D, flavicordin‑A glucoside, ethyl stearate, lignans, alkaloids andsaponins. The present review is an up‑to‑date summary of occurrence, botanical description, ethnopharmacology, bioactivity and toxicological studies related to P. macrocarpa.

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      Altaf, R., Asmawi, M. Z. B., Dewa, A., Sadikun, A., & Umar, M. I. (2013). Phytochemistry and medicinal properties of Phaleria macrocarpa (Scheff.) Boerl. extracts. Pharmacognosy Reviews, 7(13), 73–80. https://doi.org/10.4103/0973-7847.112853