Procyanidins from the bark of Prunus africana
F. Qa'dan1★★ Corresponding author
- 1School of Pharmacy, The University of Petra, P.O.Box: 961343, Amman, 11196 Jordan, Jordan.
CORRESPONDENCE
F. Qa'dan
School of Pharmacy, The University of Petra, P.O.Box: 961343, Amman, 11196 Jordan, Jordan.
Volume 1, Issue 4 · pp. 152–154 · PUBLISHED 2005 · DOI:
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ABSTRACT
From the aqueous acetone extract of the bark of Prunus africana (Hook.f.) Kalkman (Syn. Pygeum africanum Hook.f.) the flavanols catechin (1) and epicatechin (2), and the procyanidins B-1 (3), B-2 (4), B-3 (5), A-2 (6) and C-1 (7) were isolated and identified. Their structures were established as their peracetate derivatives, on the basis of chemical and spectral evidence. The 13C-NMR spectrum of the higher molecular weight polymer fraction revealed a 3',4'-dihydroxylated B-ring oxidation pattern and the 2,3-cis relative stereochemistry of the constituent flavan-3-ol units. The mean average molecular size of the polymers was estimated to be about 8 to 9 flavan-3-ol-units.
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Qa'dan, F. (2005). Procyanidins from the bark of Prunus africana. Pharmacognosy Magazine, 1(4), 152–154.