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    Article

    Ultrasound‑assisted extraction of total flavonoids from Aconitum gymnandrum

    Ling‑Li Zheng1, Dan Wang2, Yuan‑Yuan Li2, Hong‑Yan Peng2, Ming‑Yong Yuan1, Feng Gao2★★ Corresponding author

    1. 1Department of Pharmacy, The First Affiliated Hospital, Chengdu Medical College, Middle Section, Baoguang Road, Xindu Region, Chengdu 610 500, China.
    2. 2Department of Chinese Traditional Herbal, Agronomy College, Sichuan Agricultural University, Huiming Road, Wenjiang Region, Chengdu 611 130, China.

    CORRESPONDENCE

    Feng Gao

    Department of Chinese Traditional Herbal, Agronomy College, Sichuan Agricultural University, Huiming Road, Wenjiang Region, Chengdu 611 130, China.

    gaofeng@sicau.edu.cn

    Received: 21-11-2012; Revised: 06-01-2013.

    Volume 10, Issue 37s · pp. S141–S146 · PUBLISHED 21 February 2014 · DOI: 10.4103/0973-1296.127364

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Background: Aconitum gymnandrum is a Chinese traditional herb used as carminative and analgesic. In this study, A. gymnandrum was used as an experimental matrix. Materials and Methods: Optimized ultrasonic extraction technology of total flavonoids from the A. gymnandrum Maxim was studied by using the methodology of single factor and orthogonal design to study the effects of operation conditions, such as ethanol content, ultrasonic wave power, temperature, ultrasonic wave radiation time, and the ratio of sample weight to solvent volume. Result: Through the orthogonal experiment, the optimal extraction conditions were determined as follows: Ultrasonic power 100 W, ultrasonic temperature 45°C, 60% ethyl alcohol, extraction time 30 min, and solid–liquid ratio 1:20. Conclusion: Under the optimum parameters, the extraction ratio of total flavonoids from the A. gymnandrum Maxim is about 1.278%.

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      Zheng, L., Wang, D., Li, Y., Peng, H., Yuan, M., & Gao, F. (2014). Ultrasound‑assisted extraction of total flavonoids from Aconitum gymnandrum. Pharmacognosy Magazine, 10(37s), S141–S146. https://doi.org/10.4103/0973-1296.127364