Anti-Fatigue Effect of Green Tea Polyphenols (-)-Epigallocatechin-3-Gallate (EGCG)
Yu-song Teng1★, Di Wu1★ Corresponding author
- 1School of Physical Education, Liaoning Normal University, Dalian, P.R. China, China.
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Yu-song Teng
School of Physical Education, Liaoning Normal University, Dalian, P.R. China, China.
Received: 06-03-2016; Revised: 04-04-2016; Accepted: 04-04-2016.
Volume 13, Issue 50 · pp. 326–31 · PUBLISHED 18 April 2017 · DOI: 10.4103/0973-1296.204546
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ABSTRACT
Background: (-)-Epigallocatechin-3-gallate (EGCG) is the most abundant of the green tea polyphenols that exhibit a variety of bioactivities. The objective of this study was to evaluate the anti-fatigue effect of EGCG by forced swimming exercise. Materials and Methods: The mice were divided into one control group and three EGCG-treated groups. The control group was administered with distilled water and EGCG-treated groups were administered with different dose of EGCG (50, 100, and 200 mg/kg) by oral gavage for 28 days. On the last day of experiment, the forced swimming exercise was performed and corresponding biochemical parameters were measured. Results: The data showed that EGCG prolonged exhaustive swimming time, decreasing the levels of blood lactic acid, serum urea nitrogen, serum creatine kinase and malondialdehyde, which were accompanied by corresponding increase in liver and muscle glycogen contents, and superoxide dismutase, catalase, and glutathione peroxidase activities. Conclusions: This study indicated that EGCG had an anti-fatigue effect.
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Teng, Y., & Wu, D. (2017). Anti-Fatigue Effect of Green Tea Polyphenols (-)-Epigallocatechin-3-Gallate (EGCG). Pharmacognosy Magazine, 13(50), 326–31. https://doi.org/10.4103/0973-1296.204546