Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Pharmacognosy MagazineNOW IN
    Article

    Evaluation on the Skin Anti-Aging Potential of an Aqueous Extract from Oenanthe javanica (Blume) DC

    Hye‑Won Lim2, Yu‑Hua Huang2, Minsik Park3, Chang‑Jin Lim2,4★★ Corresponding author

    1. 1R and D Center, Shebah Biotech Inc.
    2. 2Department of Molecular and Cellular Biochemistry, Kangwon National University School of Medicine.
    3. 3Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.

    CORRESPONDENCE

    Chang‑Jin Lim

    Department of Molecular and Cellular Biochemistry, Kangwon National University School of Medicine.

    cjlim@kangwon.ac.kr

    Received: 08-08-2021; Revised: 04-09-2021; Accepted: 16-11-2021.

    Volume 18, Issue 77 · pp. 75–81 · PUBLISHED 28 March 2022 · DOI: 10.4103/pm.pm_366_21

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Objectives: This work aimed to primarily assess the skin anti‑aging potential of its aerial parts. Materials and Methods: The dried aerial parts of water dropwort were extracted with water under high pressure and high temperature, which produced the resultant powdered extract, named OJW. The antiradical activity of OJW was quantitated using ABTS•+ and 2,2‑Diphenyl‑1‑picrylhydrazyl (DPPH) scavenging assays. The in vitro scavenging activities of OJW against superoxide anion radical, hydrogen peroxide and nitrite ions were determined based upon spectrophotometric protocols. The anti‑elastase and anti‑hyaluronidase activities of OJW were spectrophotometrically determined. Results: The contents of total polyphenols and total flavonoids in OJW were determined to be 13.5 ± 0.3 mg gallic acid equivalent/gram OJW and 16.9 ± 0.1 mg naringin equivalent/gram OJW, respectively. OJW exhibited total antiradical activities in both ABTS•+ and DPPH scavenging assays. The scavenging activities of OJW on individual Reactive oxygen species, such as hydrogen peroxide and superoxide anion radical, and nitrite ions were convinced. OJW exerted inhibitory activities on elastase and hyaluronidase. Liquid chromatography‑tandem mass spectrometry analysis indicated the presence of two flavonoids, quercetin, and isorhamnetin, in OJW. Conclusion: O. javanica aerial parts possess skin anti‑aging potential through the antioxidant, anti‑inflammatory, and anti‑wrinkle activities.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Lim, H., Huang, Y., Park, M., & Lim, C. (2022). Evaluation on the Skin Anti-Aging Potential of an Aqueous Extract from Oenanthe javanica (Blume) DC. Pharmacognosy Magazine, 18(77), 75–81. https://doi.org/10.4103/pm.pm_366_21