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    Pharmacognosy MagazineNOW IN
    Article

    Antiulcer and antimicrobial activities of Stryphnodendron rotundifolium Mart.

    Fabiola Fernandes Galvão Rodrigues1, Brisa do Svadesvich Cabral1, Henrique Douglas Melo Coutinho1, André Luiz Herzog Cardoso1, Adriana Rolim Campos1, José Galberto Martins da Costa1★★ Corresponding author

    1. 1Laboratório de Pesquisas de Produtos Naturais, Departamento de Química Biológica, Universidade Regional do Cariri, Rua Cel. Antônio Luiz, 1161, CEP 63105-000, Crato – Ceará, Brazil.

    CORRESPONDENCE

    José Galberto Martins da Costa

    Laboratório de Pesquisas de Produtos Naturais, Departamento de Química Biológica, Universidade Regional do Cariri, Rua Cel. Antônio Luiz, 1161, CEP 63105-000, Crato – Ceará, Brazil.

    galberto@urca.br

    Volume 4, Issue 15 · pp. 193–194 · PUBLISHED 2008 · DOI:

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    The ethanolic extract of Stryphnodendron rotundifolium stem bark (EESR) was investigated for therapeutic properties using ethanol-induced ulceration in mice. Antimicrobial and preliminary phytochemical screening of the extract was also investigated. The extract (200-400 mg/kg p.o.) dose dependently reduced ethanol (0.2 mL/animal p.o.) - induced ulceration in mice. EESR showed antimicrobial activity against five bacterial species (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Shigella flexineri, Staphylococcus epidermidis) but not against the fungi Aspergillus niger. The above results show that Stryphnodendron rotundifolium bark probably contains some active ingredients that could be developed for health problems as have been claimed by traditional popular use.

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      Rodrigues, F. F. G., Cabral, B. D. S., Coutinho, H. D. M., Cardoso, A. L. H., Campos, A. R., & Costa, J. G. M. D. (2008). Antiulcer and antimicrobial activities of Stryphnodendron rotundifolium Mart.. Pharmacognosy Magazine, 4(15), 193–194.