Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes.
P Chattopadhyay1★, A.K. Wahi2, N Verma2, A Verma2, V.D. Aher2★ Corresponding author
- 1Microbiology and Cell Biology Laboratory, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
- 2Division of Pharmacognosy and PhytoChemistry, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
CORRESPONDENCE
P Chattopadhyay
Chattopadhyay P,Microbiology and Cell Biology Laboratory, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
Volume 4, Issue 15 · pp. 207–209 · PUBLISHED 2008 · DOI:
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ABSTRACT
Nitric oxide (NO) is generated in many mammalian tissues and is an important mediator of both physiological and pathological responses. The present study investigated the effect of alcoholic and aqueous extracts of whole plant of Phyllanthus fraternus Linn in NO production and platelets aggregation. Splenocytes were separated and NO production was measured. Both alcoholic and aqueous extracts showed significant increase in NO production and inhibition of platelets aggregation in chicken lymphocytes at a dose of 600 µg/ ml. The study reveals that P. fraternus may be used in asthma or in cardiovascular implications.
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Chattopadhyay, P., Wahi, A., Verma, N., Verma, A., & Aher, V. (2008). Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes.. Pharmacognosy Magazine, 4(15), 207–209.