Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Pharmacognosy MagazineNOW IN
    Article

    Secondary metabolites from the stem of Ravenia spectabilis Lindl

    Md. Mozammel Haque1★, Sufia Begum2, Md. Hossain Sohrab3, Monira Ahsan2, Choudhury M. Hasan2, Nuruddin Ahmed1, Rashedul Haque2★ Corresponding author

    1. 1Organic Research Laboratory, Department of Chemistry, Faculty of Science, Jagannath University, Dhaka-1100, Bangladesh.
    2. 2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.
    3. 3Chemical Research Division, Bangladesh Council of Scientific and Industrial Research (BCSIR) Laboratories Dhaka, Dhaka-1205, Bangladesh.

    CORRESPONDENCE

    Md. Mozammel Haque

    Organic Research Laboratory, Department of Chemistry, Faculty of Science, Jagannath University, Dhaka-1100, Bangladesh.

    Received: 18-01-2012; Revised: 25-06-2012.

    Volume 9, Issue 33 · pp. 76–80 · PUBLISHED 5 March 2013 · DOI: 10.4103/0973-1296.108147

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Background: Ravenia spectabilis is a medium tall shrub found widespread in South America. It also found in India, Pakistan, Bangladesh etc. Few alkaloid and steroid compounds were reported from the plant previously. Materials and Methods: Methanol extract from the stems of Ravenia spectabilis were partitioned into n-hexane, carbon tetrachloride, chloroform and aqueous soluble fractions, respectively. The crude methanol extract, carbon tetrachloride fraction and chloroform fraction were fractionated by column chromatography of Silica gel and Sephadex LH-20 for isolation and purification of compounds. The structures of the isolated compounds were determined by extensive NMR spectral analysis, including 2D NMR, mass spectroscopy etc. Results: Ten compounds, g-fagarine (1), ravenoline (2), N-methyl atanine (3), 2,3,3,5-tetramethyl-2,3,4,5- tetrahydrofurano [3,2-c] quinolin-4-one (4), arborinine (5), 3-geranyl indole (6), atanine (7), steroids sitosta-4- en- 3-one (8), stigmasterol (9) and 3-methoxy-4-hydroxy cinnamic acid (10) were isolated from the stems of Ravenia spectabilis. Conclusion: Compounds N-methyl atanine (3), 2,3,3,5-tetramethyl- 2,3,4,5-tetrahydrofurano [3,2-c] quinolin-4-one (4), 3-geranyl indole (6), sitosta-4-en-3-one (8) and 3-methoxy-4-hydroxy cinnamic acid (10) were isolated from this plant for the first time. 3-geranyl indole (6) was also isolated second time from natural sources.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Haque, M. M., Begum, S., Sohrab, M. H., Ahsan, M., Hasan, C. M., Ahmed, N., & Haque, R. (2013). Secondary metabolites from the stem of Ravenia spectabilis Lindl. Pharmacognosy Magazine, 9(33), 76–80. https://doi.org/10.4103/0973-1296.108147