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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Ecthyma gangrenosum-Source Reduction along with Empirical Antibiotics and Wound Care Helps to Treat Serious Infections

    A. Ramya1, M. Manoj Kumar Raja2★, E. Bhavya1, Vivekananadan K3★ Corresponding author

    1. 1Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), India.
    2. 2Department of Surgery, ESIC Hospital, India.
    3. 3Department of Pharmacy Practice, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute, Deemed to be University, Chennai, Tamil Nadu, India.

    CORRESPONDENCE

    M. Manoj Kumar Raja

    No 82,83; Natraj Nagar, Madhavaram, Chennai - 600 060, Tamil Nadu, India.

    dr.mano0611apps@gmail.com

    Received: 17-12-2019; Revised: 15-02-2020; Accepted: 06-05-2020.

    Volume 11, Issue 1 · pp. 30–32 · PUBLISHED 12 September 2020 · DOI: 10.4103/jpp.JPP_122_19

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Ecthyma gangrenosum (Eg) is a cutaneous necrotic lesion that is mostly seen in immunocompromised patients. It reflects a severe sepsis, possibly caused by Pseudomonas aeruginosa, an aerobic Gram-negative opportunistic pathogen that has a high risk of associated mortality in cases where the infection is systemic. These skin lesions may be seen on admission or can develop later. The recognition of Eg lesions permits the earliest possible introduction of the most effective antimicrobial therapy, which is a key prognostic factor for survival. A 52-year-old male patient admitted to the surgery department presented a sepsis associated green color pus discharge with pain and swelling. An empiric antibiotic therapy was prescribed. Five days after admission, pus culture was positive for Pseudomonas aeruginosa. As a result, the decision was made to continue the antibiotic therapy. Empiric therapy leads to granulation tissue formation. Eg can be treated with simple antibiotic therapy.

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      Ramya, A., Raja, M. M. K., Bhavya, E., & K, V. (2020). Ecthyma gangrenosum-Source Reduction along with Empirical Antibiotics and Wound Care Helps to Treat Serious Infections. Journal of Pharmacology and Pharmacotherapeutics, 11(1), 30–32. https://doi.org/10.4103/jpp.JPP_122_19