Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Monday Blues – Rare Cause of Hypoglycemia in a Child with Leukemia

    Gowshika Krishnakumar1, Dhaarani Jayaraman2★, Dhivyalakshmi Jeevarathnam3, Peter Prasanth Kumar Kommu4, Julius Xavier Scott1★ Corresponding author

    1. 1Department of Pediatrics, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
    2. 2Department of Pediatrics, Division of Pediatric Hemato-Oncology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
    3. 3Department of Pediatrics, Division of Pediatric Endocrinology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
    4. 4Department of Pediatrics, Pondicherry Institute of Medical Sciences, Puducherry, India.

    CORRESPONDENCE

    Dhaarani Jayaraman

    Department of Pediatrics, Division of Pediatric Hemato-Oncology, Sri Ramachandra Institute of Higher Education and Research, No. 1, Ramachandra Nagar, Porur, Chennai ‑ 600 116, Tamil Nadu, India.

    dhaaranij@yahoo.com

    Received: 24-05-2021; Revised: 05-06-2021; Accepted: 11-06-2021.

    Volume 12, Issue 2 · pp. 100–101 · PUBLISHED 17 September 2021 · DOI: 10.4103/jpp.jpp_57_21

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Hypoglycemia in a child with acute lymphoblastic leukemia (ALL) often makes the clinician think of sepsis or metabolic disturbances due to relative adrenal insufficiency with steroid withdrawal. We report a rare scenario of drug-induced hypoglycemia in a child on treatment for ALL. Recurrent symptomatic episodes of hypoglycemia in a 4-year-girl on treatment for high-risk ALL were analyzed and it was surprising to note that the episodes were noted on early hours on Monday and Sunday nights. Detailed evaluation for the etiology and the workup was not contributory. With the background of drug history for ALL maintenance and occurrence of episodes on Mondays, possibility of drug-induced hypoglycemia secondary to cotrimoxazole was considered. Dose alteration for trimethoprim-sulfamethoxazole was considered stopping the drug is not feasible. Malnutrition was attributed as the coexisting risk factor in our child.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Krishnakumar, G., Jayaraman, D., Jeevarathnam, D., Kommu, P. P. K., & Scott, J. X. (2021). Monday Blues – Rare Cause of Hypoglycemia in a Child with Leukemia. Journal of Pharmacology and Pharmacotherapeutics, 12(2), 100–101. https://doi.org/10.4103/jpp.jpp_57_21