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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Effect of Coping Strategies on Pain Intensity in Patients with Rheumatoid Arthritis

    K Rohith Chandra1, B Jeevan Kumar1,2, D Mubeen Taj1, Pavani M1, Kondaveeti Devaki3, Nunavath Raja Shekhar4, Sirisha Kommireddy5, Ajay Kumar Chittipolu6, Goutham Yerrakula7,8★★ Corresponding author

    1. 1Department of Pharmacy Practice, MB School of Pharmaceutical Science, Mohan Babu University, Rangampeta, Andhra Pradesh, INDIA.
    2. 2Current affiliation: Department of Pharmacy Practice, KL College of Pharmacy, KLEF Deemed to be University, Vaddeswaram, Andhra Pradesh, INDIA.
    3. 3Department of Pharmacology, Amity Institute of Pharmacy, Noida, Uttar Pradesh, INDIA.
    4. 4Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, The Nilgiris, Tamil Nadu, INDIA.
    5. 5Consultant Rheumatologist, Isha Super Specialty Clinics, Tirupati, Andhra Pradesh, INDIA.
    6. 6Department of Pharmaceutical Sciences, Vision College of Pharmaceutical Sciences and Research, Boduppal, Hyderabad, Telangana, INDIA.
    7. 7School of Pharmacy, Faculty of Health Sciences, JSS Academy of Higher Education and Research, Vacoas-Phoenix, Mauritius.
    8. 8Department of Pharmacology, College of Pharmacy, JSS Academy of Technical Education, Noida, Uttar Pradesh, INDIA.

    CORRESPONDENCE

    Goutham Yerrakula

    Department of Pharmacy Practice, KL College of Pharmacy, KLEF Deemed to be University, Green Fields, Vaddeswaram, Andhra Pradesh 522302, India.

    gouphd@jssuni.edu.in

    Received: 07-03-2024; Revised: 16-04-2024; Accepted: 09-05-2024.

    Volume 15, Issue 3 · pp. 277–283 · PUBLISHED 2024 · DOI: 10.1177/0976500X241263653

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease that imposes significant challenges globally. This research seeks to contribute valuable insights that can inform the development of targeted interventions, enhancing the quality of care for RA patients and potentially mitigating the broader societal burden associated with this chronic autoimmune condition. Objectives: The main objective of the current study is to investigate the demographic, psychosocial, and clinical aspects of RA patients. Materials and Methods: The study included 93 RA patients and examined their demographic characteristics, briefCoping Orientation to Problems Experienced (COPE) strategies, the prevalence of depression and anxiety, pain experiences (Mankoski Pain Scale), and diagnostic markers (Disease Activity Score [DAS-28], Rheumatoid Factor [RF], Anti-Cyclic Citrullinated Peptide [ACCP]). Results: The study revealed a bimodal age distribution, with a gender predominance aligning with established RA prevalence patterns. Patients exhibited a tendency toward adaptive coping strategies, notably religious coping, active coping, and positive reframing, with variability in maladaptive strategies. The prevalence of depression (14.0%) and anxiety (18.3%) among RA patients was consistent with documented mental health burdens. Pain experiences exhibited a heterogeneous spectrum, and diagnostic markers indicated elevated disease activity in a substantial proportion of patients, with varied distribution in RF and ACCP subcategories. Conclusion: This study provides nuanced insights into RA, emphasizing the importance of personalized coping and pain management strategies. The prevalence of mental health challenges and the spectrum of pain experiences underscore the multidimensional nature of RA, informing holistic approaches to care for enhanced patient outcomes.

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      Chandra, K. R., Kumar, B. J., Taj, D. M., M, P., Devaki, K., Shekhar, N. R., Kommireddy, S., Chittipolu, A. K., & Yerrakula, G. (2024). Effect of Coping Strategies on Pain Intensity in Patients with Rheumatoid Arthritis. Journal of Pharmacology and Pharmacotherapeutics, 15(3), 277–283. https://doi.org/10.1177/0976500X241263653