Journal of Pharmacology and Pharmacotherapeutics
Volume 15, Issue 3
2024 · pp. 213–368 · 16 articles
- Volume
- 15
- Issue
- 3
- Published
- 2024
- Pages
- 213–368
- Articles
- 16
- Sections
- 3
- ISSN
- ISSN: Print - 0976-500X, Online - 0976-5018
- Journal
- J Pharmacol. Pharmacother.
In this issue
Review Article
- Review
A Review on the Poisonous Plant Cleistanthus collinus
Raman P. Priyadharsini, Subramani Parasuraman, Sagar Puli, Ramasamy Raveendran
pp. 213–220 · DOI: 10.1177/0976500X241257741 · Published 2024
Cleistanthus collinus is a toxic plant belonging to the Euphorbiaceae family, and all parts of the plant are poisonous. It is used as suicidal, homicidal, cattle and fish poison and for inducing criminal abortion. The le…
- Review
An Overview of Indian Marine Seaweeds and their Medicinal Applications
Kavya R., Vimala Ananthy, Kartik Janardan Salwe, K. Manimekalai, Boopathi Komarasamy, Reka Deva
pp. 221–236 · DOI: 10.1177/0976500X241264899 · Published 2024
Background: Seaweeds are macroalgae containing bioactive compounds that have positively impacted the biomedical field due to polysaccharides, sterols and glycolipids, showing a diverse range of pharmacological and biolog…
- Review
Adipokine Modulation in Endometrial Hyperplasia by Polyunsaturated Fatty Acids
Athuru Supriya, Ammu V. V. V. Ravi Kiran, Praveen Thaggikuppe Krishnamurthy
pp. 237–252 · DOI: 10.1177/0976500X241259578 · Published 2024
Background: Obesity is associated with a higher prevalence of endometrial hyperplasia, thereby increasing the risk of endometrial and ovarian cancers. The precise mechanisms linking obesity to endometrial hyperplasia rem…
- Review
Neurotoxicity by Hypoxia an Intermediate Between Alpha-synuclein and Mitochondrial Dysfunction in Parkinson’s Disease
Jagdish Chand, Hannah Lalengzuali Fanai, A. S. Antony, Gomathy Subramanian
pp. 253–263 · DOI: 10.1177/0976500X241253648 · Published 2024
This review article explores the relationship between alpha-synuclein and mitochondrial dysfunction in Parkinson’s disease (PD), focusing on the role of hypoxia as an intermediate factor. The interaction between alpha-sy…
Research Article
- Article
Comparing the Effect of Intravenous Tramadol and Intravenous Nalbuphine in Addition to Midazolam for the Control of Shivering after Spinal Anesthesia
Apoorva Madem, Sravanthi Parusha, Dinakar Mallem, Indira Pacharla, Vijay Kotra, Wen Han Chooi, Rebecca Shin Yee Wong, Long Chiau Ming, Ali Saleh Alkhoshaiban, Khang Wen Goh
pp. 264–276 · DOI: 10.1177/0976500X241262076 · Published 2024
Introduction: Shivering is a common complication during neuraxial anesthesia, leading to metabolic and cardiovascular challenges. Existing treatments vary in effectiveness, and this study compares intravenous tramadol an…
- Article
Effect of Coping Strategies on Pain Intensity in Patients with Rheumatoid Arthritis
K Rohith Chandra, B Jeevan Kumar, D Mubeen Taj, Pavani M, Kondaveeti Devaki, Nunavath Raja Shekhar, Sirisha Kommireddy, Ajay Kumar Chittipolu, Goutham Yerrakula
pp. 277–283 · DOI: 10.1177/0976500X241263653 · Published 2024
Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease that imposes significant challenges globally. This research seeks to contribute valuable insights that can inform the development of targeted interve…
- Article
Exploration of Active Ingredients, Targets, and Potential Mechanisms of Er-Miao-San in the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking Technology
Lin Zhou, Jinyan Chu, Chenyue Yuan, Yong Zhao, Yuting Yan, Lin Jing, Jianlin Ren
pp. 284–297 · DOI: 10.1177/0976500X241259577 · Published 2024
Background: Er-Miao-San (EMS) is a classic prescription in Traditional Chinese Medicine (TCM) for the treatment of colorectal cancer (CRC) and has shown promising therapeutic effects in clinical practice. However, the sp…
- Article
Pharmacological Study of Guben Yifei-Tang on a Rat Model of Pneumoconiosis
Zhou Yang, Shi Wenting, Haiming Lei, Weihong Shi
pp. 298–305 · DOI: 10.1177/0976500X241259575 · Published 2024
Background: Diffuse pulmonary fibrosis is a progressively worsening lung disease that poses a serious threat to human health. Current treatment options are limited and generally ineffective. Objectives: This study aimed …
- Article
Anti-inflammatory Property of Ethanolic Extract of Cleome spinosa Leaves in an in vivo Model of Delayed-type Hypersensitivity
Torisa Roy, Tamal Mazumder, Priyanka Sharma, Tamali Roy, Tapas Chandra Nag, Samik Bindu, Subir Chandra Dasgupta, Hadida Yasmin
pp. 306–315 · DOI: 10.1177/0976500X241253645 · Published 2024
Objectives: Delayed-type hypersensitivity (DTH) reactions represent a clinically important class of immune responses that have wide-ranging implications in various health and disease conditions. The existing anti-inflamm…
- Article
Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Traditional Medicinal Compounds Against Exfoliative Toxin B from Staphylococcus aureus
Nandha Kumar Subramani, Subhashree Venugopal
pp. 316–326 · DOI: 10.1177/1266072 · Published 2024
Background: Staphylococcal scalded skin syndrome (SSSS) is a dermatological condition caused by Staphylococcus aureus, characterized by exfoliative toxin B, and its increasing resistance to conventional antibiotics neces…
- Article
Anthelmintic Activity of Alcoholic Leaf Extract of Tectona grandis
Devu B. Nair, Sujith S., Divya Rajaselvi, Aparna S. Sivapriya, Nikitha Shajan, Nisha A. R., Priya M. N.
pp. 327–335 · DOI: 10.1177/0976500X241266076 · Published 2024
Background: Helminthiasis is a major concern in the livestock sector due to the immense afflictions in the production and economy of the farmer. Chemical anthelmintics are used to combat them and parasites are acquiring …
- Article
Correlation of Hypothyroidism with Age and Comorbidities Among Women: A Cross-Sectional Study
Mufida Begum Ifthikhar, Kumudha Dhamotharaswamy
pp. 336–342 · DOI: 10.1177/0976500X241266077 · Published 2024
Background: Hypothyroidism, an endocrine disorder caused by thyroid dysfunction found to be more prevalent globally in females than in males. Young females are more prone to subclinical hypothyroidism (SCH). The study ai…
Case Report
- Article
Diabetic Brachial Plexopathy: A Case Report
Megha Hegde, Saurav Raj, Dhananjay Tikadar, Sanatkumar B. Nyamagoud
pp. 343–348 · DOI: 10.1177/0976500X241254903 · Published 2024
Diabetes is known to cause an array of central and peripheral neurological conditions. Among the neuropathic complications associated with diabetes are distal symmetrical polyneuropathy, amyotrophy, polyradiculopathy, au…
- Article
A Case Report of Tinea Infection (Dadru Kustha) with Ayurvedic Intervention
Sonia Mandal, Vinod Ade, Punam Sawarkar, Reeya Gamne, Gaurav Sawarkar, Shweta Parwe
pp. 349–354 · DOI: 10.1177/0976500X241259840 · Published 2024
Background: The most typical dermatologic disorders worldwide include tinea infections. Skin ringworm infections, such as tinea corporis and tinea cruris, are caused by Trichophyton rubrum, Epidermophyton, and Microsporu…
- Article
The Management of Bronchial Asthma (Tamak Shwasa) through Panchakarma Procedure with Ishvaku (Lagenariasiceraria) Vamana: A Case Report
Shweta Parwe, Milind Nisargandha, Anita Wanjari, Mamata Nakade
pp. 355–361 · DOI: 10.1177/0976500X241259580 · Published 2024
Background: Bronchial asthma, a hypersensitivity illness, is rising quickly in the modern world, particularly in wealthy nations. However, according to clinical features, bronchial asthma and Ayurvedic Tamaka Shwasa are …
- Article
Management of Kampavata (Parkinson’s Disease) through Panchakarma: A Successful Case Study
Sonia Mandal, Punam Sawarkar, Varinder Singh, Shweta Parwe, Gaurav Sawarkar
pp. 362–368 · DOI: 10.1177/0976500X241266049 · Published 2024
Introduction: Parkinson’s disease (PD) affects the central nervous system and is primarily characterized by the degeneration of dopamine-producing cells in the substantia nigra. Early signs include tremor, rigidity, brad…