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    LungCTSeg-Net: Lung HRCT Image Segmentation Using Learning Approach

    Vanita Dnyandev Jadhav1, Lalit Vasantrao Patil2 Corresponding author

    1. 1Department of Computer Engineering, SKNCOE, Vadgaon, Pune, Maharashtra, INDIA.
    2. 2Department of Information Technology, SKNCOE, Vadgaon, Pune, Maharashtra, INDIA.

    CORRESPONDENCE

    Vanita Dnyandev Jadhav

    Department of Computer Engineering, SKNCOE, Vadgaon, Pune, Maharashtra, INDIA.

    vdjadhav@coe.sveri.ac.in

    Received: 15-10-2024; Accepted: 26-03-2025.

    Volume 17, Issue 1 · pp. 135–144 · PUBLISHED 2026 · DOI: 10.1177/0976500X251336602

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Background: Automatic lung segmentation is a crucial initial step in computer-aided lung computed tomography (CT) diagnosis. However, existing methods struggle to achieve accurate segmentation in the presence of dense abnormalities, limiting their clinical reliability. Objectives: This research aims to improve lung segmentation accuracy by proposing a novel generative adversarial network (GAN)-founded method, named LungCTSeg-Net, designed to effectively segment lungs even in the presence of dense abnormalities. Materials and Methods: The projected LungCTSeg-Net processes input lung CT pieces through a series of encoders, converting them into feature plots. A specialized multi-scale dense feature extraction (MSDFE) module abstracts multi-scale features from these encoded maps. The segmentation map is generated using decoders, with repeated down-sampling and upsampling to ensure invariance to the size of dense anomalies. The method is tested on the publicly available interstitial lung disease (ILD) dataset. Results: Experimental results demonstrate that LungCTSeg-Net achieves robust performance regardless of the presence of dark anomalies in lung CT scans, outperforming existing approaches in segmentation accuracy. Conclusion: The proposed LungCTSeg-Net approach improves lung segmentation accuracy in challenging cases with dense anomalies. The combination of multi-scale feature extraction and GAN architecture enhances the model’s capability to capture composite lung constructions, supporting more reliable computer-aided lung CT diagnosis.

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      Jadhav, V. D., & Patil, L. V. (2026). LungCTSeg-Net: Lung HRCT Image Segmentation Using Learning Approach. Journal of Pharmacology and Pharmacotherapeutics, 17(1), 135–144. https://doi.org/10.1177/0976500X251336602