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    Vitamin D Deficiency in Al-Madinah AlMunawwarah: A Cross-sectional Study of Prevalence Among Saudi and Non-Saudi Population

    Muhammed Hassan Nasr1, Noordin Othman2,3, Bassam Abdulrasool Hassan4, Mahmathi Karuppannan4, Noorizan Binti Abdulaziz4, Mohammed Ahmed Alsarani5, Shalam Mohamed Hussain1 Corresponding author

    1. 1Clinical Pharmacy Department, Al Rayan National College of Health Sciences and Nursing, Al Rayan Colleges, Al-Madinah Al-Munawwarah, Medina Province, SAUDI ARABIA.
    2. 2Department of Clinical and Hospital Pharmacy, Faculty of Pharmacy, Taibah University, Al-Madinah Al-Munawwarah, Medina Province, SAUDI ARABIA.
    3. 3Department of Clinical Pharmacy, School of Pharmacy, Management and Science University, University Drive, Off Persiaran Olahraga, Shah Alam, Selangor, MALAYSIA.
    4. 4Clinical Pharmacy Department, Faculty of Pharmacy, Universiti Teknologi MARA, Shah Alam, Selangor, MALAYSIA.
    5. 5Laboratory Department, Medical Care Unit, Taibah University, AlMadinah Al-Munawwarah, Medina Province, SAUDI ARABIA.

    CORRESPONDENCE

    Muhammed Hassan Nasr

    Clinical Pharmacy Department, Al Rayan National College of Health Sciences and Nursing, Al Rayan Colleges, Al-Madinah Al-Munawwarah, Medina Province, SAUDI ARABIA.

    mh.nasr@amc.edu.sa

    Received: 25-01-2025; Accepted: 26-03-2025.

    Volume 17, Issue 1 · pp. 69–76 · PUBLISHED 2026 · DOI: 10.1177/0976500X251339561

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Background: Vitamin D deficiency poses significant health risks globally, impacting bone health and immune function. In Saudi Arabia, where environmental and lifestyle factors limit sun exposure, vitamin D deficiency is especially prevalent. This study assesses vitamin D deficiency in Al-Madinah, focusing on differences between Saudi nationals and non-Saudi residents. Objectives: The primary aim was to determine the prevalence of vitamin D deficiency among Saudis and non-Saudis and identify lifestyle and dietary factors contributing to deficiency. Materials and Methods: Conducted from October 2017 to May 2018, this cross-sectional study included 65 non-diabetic male participants aged 18–65, divided into two groups: Saudi (n = 33) and non-Saudi (n = 32). Exclusion criteria included conditions affecting vitamin D metabolism. Data were collected on demographics, dietary habits, sun exposure, and anthropometric measurements. Serum 25-hydroxyvitamin D levels were measured, and logistic regression was used to identify predictors of deficiency. Results: Vitamin D deficiency was significantly higher in Saudis (91%) than in non-Saudis (47%). Limited sun exposure, lower intake of vitamin D-rich foods, and occupation type were associated with higher deficiency rates among Saudis. Logistic regression revealed that occupation was a positive predictor, while liver consumption was a negative predictor of deficiency. Conclusion: This study highlights the urgent need for targeted public health interventions in Saudi Arabia to address vitamin D deficiency, recommending dietary changes and vitamin D supplementation. Further research should investigate genetic and environmental factors affecting vitamin D levels across different populations in the region.

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      Nasr, M. H., Othman, N., Hassan, B. A., Karuppannan, M., Abdulaziz, N. B., Alsarani, M. A., & Hussain, S. M. (2026). Vitamin D Deficiency in Al-Madinah AlMunawwarah: A Cross-sectional Study of Prevalence Among Saudi and Non-Saudi Population. Journal of Pharmacology and Pharmacotherapeutics, 17(1), 69–76. https://doi.org/10.1177/0976500X251339561