Hepatoprotective activity of active fractions of Thespesia lampas Dalz and Gibs (Malvaceae)

ABSTRACT

In the absence of satisfactory treatment using conventional medicine, treatment of liver disorders remains as one of the major medical problems.[1] Numerous medicinal plants are used in local health traditions to treat liver disorders. [1] In the recent past, studies have shown varying levels of hepatoprotective properties in traditional plants found in Kerala, India, such as Phyllanthus maderaspatensis, Phyllanthus rheedii, Thespesia populena, Momordica subangulata, Naregamia alata, Lygodium flexuosum, Cheilanthes farinosa, Physalis peruviana, and Trichopus zeylanicus.[2-6] However, many medicinal plants used in remote villages and tribal pockets of Kerala remain to be studied. Thespesia lampas Dalz. and Gibs (family Malvaceae) is one such plant. This plant root is used in folklore medicine to treat liver diseases in Attapadi Hills of Western Ghats, Kerala. In traditional medicine, its roots and fruits are used for treating gonorrhea, jaundice, and syphilis. Studies have shown that the plant possesses anti-microbial, antioxidant, anti-lipoxygenase, anti-hyperlipidaemic, and anthelmintic activities. The traditional use of this plant as a hepato- protective agent has not been verified. This study was carried out to get insights into the utility of T. lampas to develop a satisfactory hepatoprotective medicine.

KEYWORDS

• Research Letters

Showing references and in-text citations exactly as published.

Cite this article

• DOI10.4103/0976-500X.103691Copy

RELATED ARTICLES

Matched on volume, issue, section and article type within J Pharmacol. Pharmacother..

• Article · VOLUME 3, ISSUE 4Reporting of adverse drug reactions in clinical trials published in Indian Medical/Dental journalsPurav Mody, Tamoghona Biswas, Jaykaran Charan, Deval Parikh · pp. 325–326Research LettersSame type: ArticleSame issue
• Article · VOLUME 3, ISSUE 4Platelet aggregation inducing activity of Ficus racemosa stem bark extractsFaiyaz Ahmed, Kumar S., Asna Urooj, Kemparaju K. · pp. 329–330Research LettersSame type: ArticleSame issue
• Article · VOLUME 3, ISSUE 4Effect of rifampicin and erythromycin on the initiation of galactose induced cataract in ratsRaj Rajeshwari R. Patil, Pratibha S. Worlikar, Amol B. Chaudhari, Ozhukil K. Radhakrishnan, Rajendra P. Gupta, Saurabh Puri · pp. 330–332Research LettersSame type: ArticleSame issue
• Article · VOLUME 3, ISSUE 3A retrospective study of extrapyramidal syndromes with second generation antipsychotics in the psychiatric unit of a tertiary care teaching hospitalKingshuk Lahon, Harsha M Shetty, Amith Paramel, Gyaneshwar Sharma · pp. 266–268Research LettersSame type: ArticleVolume 3