Cover: Journal of Pharmacology and Pharmacotherapeutics
Journal of Pharmacology and Pharmacotherapeutics
Volume 3, Issue 4
2012 · pp. 297–355 · 20 articles
- Volume
- 3
- Issue
- 4
- Published
- 2012
- Pages
- 297–355
- Articles
- 20
- Sections
- 9
- ISSN
- ISSN: Print - 0976-500X, Online - 0976-5018
- Journal
- J Pharmacol. Pharmacother.
In this issue
News and Views
- Article
Old wine, old bottle, new customer
2012;345:e4260. 2012;345:e4260.
pp. 349–350 · DOI: 10.4103/0976-500X.103700 · Published 2012
It has been roughly estimated that it would take about 4 h for injured soldiers to receive a blood transfusion at a hospital. Researchers at Massachusetts General Hospital wondered whether histone deacetylase (HDAC) inhi…
- Article
One more option to void
Sivagnanam G
pp. 350–350 · DOI: · Published 2012
Pendrin is expressed on the cells of distal convoluted tubule and the collecting duct. It is involved in Cl-/HCO3- exchange (mediates HCO3- secretion and Cl- absorption) and has been demonstrated to play an important rol…
Editorial
- Forum Article
Ethics of expert opinion and the observations of the department-related parliamentary standing committee on the CDSCO
Amar Jesani
pp. 297–299 · DOI: 10.4103/0976-500X.103684 · Published 2012
On May 8, 2012, the Department Related Parliamentary Standing Committee (henceforth Committee) presented to the Parliament its 59th report on the functioning of Central Drugs Standard Control Organization (CDSCO) in the …
Review Article
- Review
Vitamin D for prevention of respiratory tract infections: A systematic review and meta-analysis
Jaykaran Charan, Jagdish P. Goyal, Deepak Saxena, Preeti Yadav
pp. 300–303 · DOI: 10.4103/0976-500X.103685 · Published 2012
Objectives: To explore the effect of vitamin D supplementation in prevention of respiratory tract infections on the basis of published clinical trials. Materials and Methods: Clinical trials were searched from various el…
Research Paper
- Article
The incidence and clinical relevance of drug interactions in pediatrics
Hasime Qorraj-Bytyqi, Rexhep Hoxha, Shaip Krasniqi, Elton Bahtiri, Valon Kransiqi
pp. 304–307 · DOI: 10.4103/0976-500X.103686 · Published 2012
Objective: To investigate the prevalence of the major drug interactions in children and verify the rate and profile of drug interactions in hospitalized pediatric patients. Materials and Methods: A retrospective study wa…
- Article
Intensive monitoring of adverse drug reactions in hospitalized patients of two medical units at a tertiary care teaching hospital
Maulik S. Doshi, Prakruti P. Patel, Samidh P. Shah, Ram K Dikshit
pp. 308–313 · DOI: 10.4103/0976-500X.103687 · Published 2012
Objective: To detect incidence of adverse drug reactions (ADRs) in hospitalized patients and to assess their causality, seriousness, preventability, and the possible economic impact. Materials and Methods: This was a pro…
- Article
Comparison of efficacy and safety of two parenteral iron preparations in pregnant women
Dhanani Jatin V., Ganguly B. P., Chauhan L. N.
pp. 314–319 · DOI: 10.4103/0976-500X.103688 · Published 2012
Objective: To compare the efficacy and safety with a fixed dose of two parenteral iron preparations, iron sucrose complex and iron sorbitol citric acid as per the current practice. Materials and Methods: A prospective ra…
- Article
Comparison of the effectiveness and safety of cefpodoxime and ciprofloxacin in acute exacerbation of chronic suppurative otitis media: A randomized, open-labeled, phase IV clinical trial
Arijit Ghosh, Utpal Jana, Ajoy Khaowas, Saumik Das, Ananya Mandal, Nina Das
pp. 320–324 · DOI: 10.4103/0976-500X.103689 · Published 2012
Objective: To compare the effectiveness and safety of cefpodoxime and ciprofloxacin for the treatment of mild to moderate cases of acute exacerbation of chronic suppurative otitis media (AECSOM). Materials and Methods: A…
Research Letters
- Article
Reporting of adverse drug reactions in clinical trials published in Indian Medical/Dental journals
Purav Mody, Tamoghona Biswas, Jaykaran Charan, Deval Parikh
pp. 325–326 · DOI: 10.4103/0976-500X.103690 · Published 2012
Every year, a large number of clinical trials studying pharmacological agents are published in the Indian medical/ dental Literature. Data on potential adverse drug reactions (ADRs) occurring during such studies needs to…
- Article
Hepatoprotective activity of active fractions of Thespesia lampas Dalz and Gibs (Malvaceae)
S. Stephen Ambrose, P. Solairaj, A. Subramoniam
pp. 326–328 · DOI: 10.4103/0976-500X.103691 · Published 2012
In the absence of satisfactory treatment using conventional medicine, treatment of liver disorders remains as one of the major medical problems.[1] Numerous medicinal plants are used in local health traditions to treat l…
- Article
Platelet aggregation inducing activity of Ficus racemosa stem bark extracts
Faiyaz Ahmed, Kumar S., Asna Urooj, Kemparaju K.
pp. 329–330 · DOI: 10.4103/0976-500X.103692 · Published 2012
Blood platelet activation and aggregation play an important physiological role in the hemostasis and it is well established that many cardiovascular disorders are linked to an abnormal excessive activation of platelets. …
- Article
Effect of rifampicin and erythromycin on the initiation of galactose induced cataract in rats
Raj Rajeshwari R. Patil, Pratibha S. Worlikar, Amol B. Chaudhari, Ozhukil K. Radhakrishnan, Rajendra P. Gupta, Saurabh Puri
pp. 330–332 · DOI: 10.4103/0976-500X.103693 · Published 2012
Cataract is the leading cause of blindness with a number of risk factors such as aging, genetic, steroids, nitric oxide, diabetes, ultraviolet radiation and smoking. An increased incidence of cataract is associated with …
Case Report
- Article
Insulin glargine overdose
Fatma Sarı Doğan, Özge Ecmel Onur, Arzu Denizbaşı Altınok, Özlem Güneysel
pp. 333–335 · DOI: 10.4103/0976-500X.103694 · Published 2011
Insulin glargine is a long acting novel recombinant human insulin analogue indicated to improve glycemic control, in adults and children with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus. The time…
- Article
Toxic epidermal necrolysis due to lamotrigine in a pediatric patient
Manish J. Barvaliya, Mahendra K. Patel, Tejas K. Patel, C. B. Tripathi
pp. 336–338 · DOI: 10.4103/0976-500X.103695 · Published 2012
A 12-year-male child developed toxic epidermal necrolysis (TEN) probably due to lamotrigine. The patient was on antiepileptic therapy (sodium valproate and clonazepam) since 6–7 months, and lamotrigine was added in the r…
- Article
Ciprofloxacin-induced erythema multiforme
Shilpashree H. S., Shriprasad Sarapur
pp. 339–341 · DOI: 10.4103/0976-500X.103696 · Published 2012
Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. One of the side effects of c…
- Article
Complete heart block in a neutropenic patient with aspergillosis: An unusual adverse effect of caspofungins
Sasmita Biswal
pp. 342–344 · DOI: 10.4103/0976-500X.103697 · Published 2012
We present a case of complete heart block (CHB) in a 58‑year‑old female patient with acute myeloid leukemia (AML) with no past history of cardiac disease, who received caspofungin in the treatment of disseminated fungal …
- Article
Anabolic androgenic steroids in delayed diagnosis of tuberculosis
Suneet K. Upadhyaya, Archana Sharma, Deependra K. Rai, Vijay Thawani
pp. 345–347 · DOI: 10.4103/0976-500X.103698 · Published 2012
This is the first case report depicting masking of symptoms of intestinal tuberculosis by anabolic androgenic steroids (AAS) causing delay in diagnosis which lead to a major surgery. Negative tuberculosis skin test (TST)…
Correspondence
- Article
Acetic acid induced painful endogenous infliction in writhing test on mice
Shivaji P. Gawade
pp. 348–348 · DOI: 10.4103/0976-500X.103699 · Published 2012
Writhing test is a chemical method used to induce pain of peripheral origin by injection of irritant principles like phenylquinone, acetic acid in mice. Analgesic activity of the test compound is inferred from decrease i…
Webwise
- Article
Protein data bank
S. Parasuraman
pp. 351–2 · DOI: 10.4103/0976-500X.103704 · Published 2012
Research Collaborators for structural Bioinformatics Protein Data Bank (RCBS PDB) began in 1970’s by group of the young crystallographers, including Edgar Meyer, Gerson Coheon and Helen M Berman.[1] The project was initi…
Molecules of the Millennium
- Article
Istaroxime: A rising star in acute heart failure
Suruchi Aditya, Aditya Rattan
pp. 353–355 · DOI: 10.4103/0976-500X.103705 · Published 2012
Heart failure in India is a growing epidemic. Around 30 to 40% of patients die from heart failure within one year of receiving the diagnosis. Currently available inotropes have not only failed to show consistent results …
