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    Phcog.Net JOURNAL OF PHARMACOLOGY AND PHARMACOTHERAPEUTICS Volume 3 · Issue 4 2012 · pp. 297–355
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    Cover: Journal of Pharmacology and Pharmacotherapeutics

    Journal of Pharmacology and Pharmacotherapeutics

    Volume 3, Issue 4

    2012 · pp. 297–355 · 20 articles

    Volume
    3
    Issue
    4
    Published
    2012
    Pages
    297–355
    Articles
    20
    Sections
    9
    ISSN
    ISSN: Print - 0976-500X, Online - 0976-5018
    Journal
    J Pharmacol. Pharmacother.

    In this issue

    News and Views

    1. Article

      Old wine, old bottle, new customer

      2012;345:e4260. 2012;345:e4260.

      pp. 349–350 · DOI: 10.4103/0976-500X.103700 · Published 2012

      It has been roughly estimated that it would take about 4 h for injured soldiers to receive a blood transfusion at a hospital. Researchers at Massachusetts General Hospital wondered whether histone deacetylase (HDAC) inhi

    2. Article

      One more option to void

      Sivagnanam G

      pp. 350–350 · DOI: · Published 2012

      Pendrin is expressed on the cells of distal convoluted tubule and the collecting duct. It is involved in Cl-/HCO3- exchange (mediates HCO3- secretion and Cl- absorption) and has been demonstrated to play an important rol

    Editorial

    1. Forum Article

      Ethics of expert opinion and the observations of the department-related parliamentary standing committee on the CDSCO

      Amar Jesani

      pp. 297–299 · DOI: 10.4103/0976-500X.103684 · Published 2012

      On May 8, 2012, the Department Related Parliamentary Standing Committee (henceforth Committee) presented to the Parliament its 59th report on the functioning of Central Drugs Standard Control Organization (CDSCO) in the

    Review Article

    1. Review

      Vitamin D for prevention of respiratory tract infections: A systematic review and meta-analysis

      Jaykaran Charan, Jagdish P. Goyal, Deepak Saxena, Preeti Yadav

      pp. 300–303 · DOI: 10.4103/0976-500X.103685 · Published 2012

      Objectives: To explore the effect of vitamin D supplementation in prevention of respiratory tract infections on the basis of published clinical trials. Materials and Methods: Clinical trials were searched from various el

    Research Paper

    1. Article

      The incidence and clinical relevance of drug interactions in pediatrics

      Hasime Qorraj-Bytyqi, Rexhep Hoxha, Shaip Krasniqi, Elton Bahtiri, Valon Kransiqi

      pp. 304–307 · DOI: 10.4103/0976-500X.103686 · Published 2012

      Objective: To investigate the prevalence of the major drug interactions in children and verify the rate and profile of drug interactions in hospitalized pediatric patients. Materials and Methods: A retrospective study wa

    2. Article

      Intensive monitoring of adverse drug reactions in hospitalized patients of two medical units at a tertiary care teaching hospital

      Maulik S. Doshi, Prakruti P. Patel, Samidh P. Shah, Ram K Dikshit

      pp. 308–313 · DOI: 10.4103/0976-500X.103687 · Published 2012

      Objective: To detect incidence of adverse drug reactions (ADRs) in hospitalized patients and to assess their causality, seriousness, preventability, and the possible economic impact. Materials and Methods: This was a pro

    3. Article

      Comparison of efficacy and safety of two parenteral iron preparations in pregnant women

      Dhanani Jatin V., Ganguly B. P., Chauhan L. N.

      pp. 314–319 · DOI: 10.4103/0976-500X.103688 · Published 2012

      Objective: To compare the efficacy and safety with a fixed dose of two parenteral iron preparations, iron sucrose complex and iron sorbitol citric acid as per the current practice. Materials and Methods: A prospective ra

    4. Article

      Comparison of the effectiveness and safety of cefpodoxime and ciprofloxacin in acute exacerbation of chronic suppurative otitis media: A randomized, open-labeled, phase IV clinical trial

      Arijit Ghosh, Utpal Jana, Ajoy Khaowas, Saumik Das, Ananya Mandal, Nina Das

      pp. 320–324 · DOI: 10.4103/0976-500X.103689 · Published 2012

      Objective: To compare the effectiveness and safety of cefpodoxime and ciprofloxacin for the treatment of mild to moderate cases of acute exacerbation of chronic suppurative otitis media (AECSOM). Materials and Methods: A

    Research Letters

    1. Article

      Reporting of adverse drug reactions in clinical trials published in Indian Medical/Dental journals

      Purav Mody, Tamoghona Biswas, Jaykaran Charan, Deval Parikh

      pp. 325–326 · DOI: 10.4103/0976-500X.103690 · Published 2012

      Every year, a large number of clinical trials studying pharmacological agents are published in the Indian medical/ dental Literature. Data on potential adverse drug reactions (ADRs) occurring during such studies needs to

    2. Article

      Hepatoprotective activity of active fractions of Thespesia lampas Dalz and Gibs (Malvaceae)

      S. Stephen Ambrose, P. Solairaj, A. Subramoniam

      pp. 326–328 · DOI: 10.4103/0976-500X.103691 · Published 2012

      In the absence of satisfactory treatment using conventional medicine, treatment of liver disorders remains as one of the major medical problems.[1] Numerous medicinal plants are used in local health traditions to treat l

    3. Article

      Platelet aggregation inducing activity of Ficus racemosa stem bark extracts

      Faiyaz Ahmed, Kumar S., Asna Urooj, Kemparaju K.

      pp. 329–330 · DOI: 10.4103/0976-500X.103692 · Published 2012

      Blood platelet activation and aggregation play an important physiological role in the hemostasis and it is well established that many cardiovascular disorders are linked to an abnormal excessive activation of platelets.

    4. Article

      Effect of rifampicin and erythromycin on the initiation of galactose induced cataract in rats

      Raj Rajeshwari R. Patil, Pratibha S. Worlikar, Amol B. Chaudhari, Ozhukil K. Radhakrishnan, Rajendra P. Gupta, Saurabh Puri

      pp. 330–332 · DOI: 10.4103/0976-500X.103693 · Published 2012

      Cataract is the leading cause of blindness with a number of risk factors such as aging, genetic, steroids, nitric oxide, diabetes, ultraviolet radiation and smoking. An increased incidence of cataract is associated with

    Case Report

    1. Article

      Insulin glargine overdose

      Fatma Sarı Doğan, Özge Ecmel Onur, Arzu Denizbaşı Altınok, Özlem Güneysel

      pp. 333–335 · DOI: 10.4103/0976-500X.103694 · Published 2011

      Insulin glargine is a long acting novel recombinant human insulin analogue indicated to improve glycemic control, in adults and children with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus. The time

    2. Article

      Toxic epidermal necrolysis due to lamotrigine in a pediatric patient

      Manish J. Barvaliya, Mahendra K. Patel, Tejas K. Patel, C. B. Tripathi

      pp. 336–338 · DOI: 10.4103/0976-500X.103695 · Published 2012

      A 12-year-male child developed toxic epidermal necrolysis (TEN) probably due to lamotrigine. The patient was on antiepileptic therapy (sodium valproate and clonazepam) since 6–7 months, and lamotrigine was added in the r

    3. Article

      Ciprofloxacin-induced erythema multiforme

      Shilpashree H. S., Shriprasad Sarapur

      pp. 339–341 · DOI: 10.4103/0976-500X.103696 · Published 2012

      Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. One of the side effects of c

    4. Article

      Complete heart block in a neutropenic patient with aspergillosis: An unusual adverse effect of caspofungins

      Sasmita Biswal

      pp. 342–344 · DOI: 10.4103/0976-500X.103697 · Published 2012

      We present a case of complete heart block (CHB) in a 58‑year‑old female patient with acute myeloid leukemia (AML) with no past history of cardiac disease, who received caspofungin in the treatment of disseminated fungal

    5. Article

      Anabolic androgenic steroids in delayed diagnosis of tuberculosis

      Suneet K. Upadhyaya, Archana Sharma, Deependra K. Rai, Vijay Thawani

      pp. 345–347 · DOI: 10.4103/0976-500X.103698 · Published 2012

      This is the first case report depicting masking of symptoms of intestinal tuberculosis by anabolic androgenic steroids (AAS) causing delay in diagnosis which lead to a major surgery. Negative tuberculosis skin test (TST)

    Correspondence

    1. Article

      Acetic acid induced painful endogenous infliction in writhing test on mice

      Shivaji P. Gawade

      pp. 348–348 · DOI: 10.4103/0976-500X.103699 · Published 2012

      Writhing test is a chemical method used to induce pain of peripheral origin by injection of irritant principles like phenylquinone, acetic acid in mice. Analgesic activity of the test compound is inferred from decrease i

    Webwise

    1. Article

      Protein data bank

      S. Parasuraman

      pp. 351–2 · DOI: 10.4103/0976-500X.103704 · Published 2012

      Research Collaborators for structural Bioinformatics Protein Data Bank (RCBS PDB) began in 1970’s by group of the young crystallographers, including Edgar Meyer, Gerson Coheon and Helen M Berman.[1] The project was initi

    Molecules of the Millennium

    1. Article

      Istaroxime: A rising star in acute heart failure

      Suruchi Aditya, Aditya Rattan

      pp. 353–355 · DOI: 10.4103/0976-500X.103705 · Published 2012

      Heart failure in India is a growing epidemic. Around 30 to 40% of patients die from heart failure within one year of receiving the diagnosis. Currently available inotropes have not only failed to show consistent results