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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Diclofenac induced acute renal failure in a decompensated elderly patient

    Pallavi Dhanvijay1★, Arup K. Misra1, Sushil K. Varma1★ Corresponding author

    1. 1Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra, India Case Report.

    CORRESPONDENCE

    Pallavi Dhanvijay

    Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra, India Case Report.

    pallavi.dhanvijay@gmail.com

    Volume 4, Issue 2 · pp. 155–157 · PUBLISHED 2013 · DOI: 10.4103/0976-500X.110916

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Non‑steroidal anti‑inflammatory drugs (NSAIDs) are one of the most commonly prescribed drugs in post‑operative period worldwide. Their nephrotoxic effects are documented and accounts for around 15.5% of all cases of drug induced renal failure. Acute renal failure following NSAIDs usage are reported in volume depleted patients which is further precipitated by co‑morbid conditions like hypertension and various drug interactions that increase plasma level of NSAIDs and worsens the condition. This highlights the importance of hydration in post‑operative period as well as assessment of co‑morbid conditions before administration of NSAIDs to prevent acute renal failure.

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      Dhanvijay, P., Misra, A. K., & Varma, S. K. (2013). Diclofenac induced acute renal failure in a decompensated elderly patient. Journal of Pharmacology and Pharmacotherapeutics, 4(2), 155–157. https://doi.org/10.4103/0976-500X.110916