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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Adverse Drug Reactions at an Addiction Psychiatry Center: A Cross‑sectional Analysis

    Siddharth Sarkar1★, Rakesh K. Chadda1, Anusha Thota2, Naveen Kumar Dhagudu1, Thota Prasad2★ Corresponding author

    1. 1Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, India.
    2. 2Pharmacovigilance Programme of India, Indian Pharmacopoeia Commission (IPC), Ghaziabad, Uttar Pradesh, India.

    CORRESPONDENCE

    Siddharth Sarkar

    Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, India.

    sidsarkar22@gmail.com

    Received: 31-03-2018; Revised: 31-05-2018; Accepted: 18-06-2018.

    Volume 9, Issue 2 · pp. 104–108 · PUBLISHED 2018 · DOI: 10.4103/jpp.JPP_41_18

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Objective: To perform a cross sectional analysis of anticipated and unanticipated adverse drug reactions occurring at an addiction psychiatry center. Materials and Methods: This observational analysis presents data on the ADRs reported by the health‑care professionals at a tertiary care public‑funded treatment center. The types of ADRs encountered over a period of 12 months are presented along. Results: A total of 251 ADRs were encountered in patients with substance use disorders. Of them, 23% were unlabeled adverse reactions. At the center, tramadol was the most common medication implicated for ADR, followed by naltrexone and disulfiram. The most common adverse event reported was loss of appetite (n = 26). According to the system organ classification, gastrointestinal (18.7%) and psychiatric symptoms (18.7%) were the most common systems implicated. Conclusion: The current findings provide opportunities for sensitization of health‑care professionals. This will help in promoting safer drug use in the field of addiction psychiatry.

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      Sarkar, S., Chadda, R. K., Thota, A., Dhagudu, N. K., & Prasad, T. (2018). Adverse Drug Reactions at an Addiction Psychiatry Center: A Cross‑sectional Analysis. Journal of Pharmacology and Pharmacotherapeutics, 9(2), 104–108. https://doi.org/10.4103/jpp.JPP_41_18