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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Frequency of Chemotherapy Medication Errors: A Systematic Review

    Ramkumar Ashokkumar1, Sureshkumar Srinivasamurthy2, Janet J. Kelly3, Scott C. Howard4, Subramani Parasuraman5, Chakradhara Rao S. Uppugunduri6★★ Corresponding author

    1. 1Department of Finance, Hospital Corporation of America, Foster City, California.
    2. 2Department of Pharmacology, Ras Al Khaimah College of Medical Sciences, Ras Al Khaimah Medical and Health Sciences University, United Arab Emirates.
    3. 3Public Health Research and Surveillance, Independent Epidemiology Contractor, Kaneohe, Hawaii.
    4. 4Department of Acute and Critical Care, College of Nursing, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.
    5. 5Department of Pharmacology, Faculty of Pharmacy, AIMST University, 08100 Bedong, Kedah, Malaysia.
    6. 6Department of Pediatrics, CANSEARCH Research Laboratory, University Hospitals of Geneva, University of Geneva, Geneva, Switzerland.

    CORRESPONDENCE

    Chakradhara Rao S. Uppugunduri

    Department of Pediatrics, CANSEARCH Research Laboratory, University Hospitals of Geneva, University of Geneva, Geneva, Switzerland.

    Chakradhara.Uppugunduri@unige.ch

    Received: 08-05-2018; Revised: 12-06-2018; Accepted: 14-07-2018.

    Volume 9, Issue 2 · pp. 86–91 · PUBLISHED 2018 · DOI: 10.4103/jpp.JPP_61_18

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Objective: To synthesize peer‑reviewed knowledge on the frequency of different types of chemotherapy medication errors. Methods: The data were collected from studies published between January 1, 2000, and March 3, 2018, and are identified through online resources such as Medline/PubMed, PubMed Central, Agency for Healthcare Research, and Quality and the Cochrane Library. The manuscripts published in peer‑reviewed scientific journals in English language were included in the study. Initially, 19,723 articles were retrieved and finally 11 were found to be eligible to include in the review and were assessed for quality. Error percentages were calculated from the ratio of error type (numerator) to sample size (denominator: medication orders or prescriptions). Results: Overall, the chemotherapy medication errors ranged from 0.004% to 41.6% among various studies. Chemotherapy medication errors ranged from 0.1% to 24.6% in prescribing, 0.40% to 0.50% in preparation, 0.03% in dispensing, and 0.02% to 0.10% in administering phases. Conclusion: Prescribing phase had the highest number of chemotherapy medication errors reported, and least was reported during dispensing phase. We also noticed a need for harmonization for reporting of medication errors.

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      Ashokkumar, R., Srinivasamurthy, S., Kelly, J. J., Howard, S. C., Parasuraman, S., & Uppugunduri, C. R. S. (2018). Frequency of Chemotherapy Medication Errors: A Systematic Review. Journal of Pharmacology and Pharmacotherapeutics, 9(2), 86–91. https://doi.org/10.4103/jpp.JPP_61_18