Cover: Journal of Pharmacology and Pharmacotherapeutics
Journal of Pharmacology and Pharmacotherapeutics
Volume 10, Issue 2
2019 · pp. 45–74 · 6 articles
- Volume
- 10
- Issue
- 2
- Published
- 2019
- Pages
- 45–74
- Articles
- 6
- Sections
- 3
- ISSN
- ISSN: Print - 0976-500X, Online - 0976-5018
- Journal
- J Pharmacol. Pharmacother.
In this issue
Editorial
- Forum Article
Of Mice and Men: The Murine Intrigues in Drug Discovery
M. K. Unnikrishnan
pp. 45–6 · DOI: 10.4103/jpp.JPP_40_19 · Published 2019
Medicine is a science of uncertainty and an art of probability. — William Osler Animal models occupy a central position in drug discovery. In vivo experiments are the sine qua non for identifying basic pathophysiological…
Research Paper
- Article
Myocardial Preconditioning Potential of Hedgehog Activator Purmorphamine (Smoothened Receptor Agonist) against Ischemia‑Reperfusion in Deoxycortisone Acetate Salt‑Induced Hypertensive Rat Hearts
Himanshi Khera, Anupam Awasthi, Sidharth Mehan
pp. 47–56 · DOI: 10.4103/jpp.JPP_8_19 · Published 2019
Aim: To investigate the myocardial preconditioning potential of hedgehog activator smoothened (SMO) receptor agonist purmorphamine (PUR) against ischemia‑reperfusion (I/R) injury in deoxycortisone acetate (DOCA) salt‑ind…
- Article
Transdermal Buprenorphine versus Intramuscular Diclofenac for Postoperative Analgesia following Upper Abdominal Surgery under General Anesthesia: A Randomized Controlled Trial
Sandip Roy Basunia, Baisakhi Laha, Avijit Hazra
pp. 57–62 · DOI: 10.4103/jpp.JPP_6_19 · Published 2019
Aim: To compare the post-operative analgesic effect of of buprenorphine 20 µg/h patch with diclofenac 75 mg intramuscular injection following upper abdominal surgery under general anesthesia (GA). Materials and Methods: …
- Article
Potential Drug–Drug Interactions in the Pediatric Intensive Care Unit of a Tertiary Care Hospital
Chandini Rao, Varadaraj Shenoy, Padmaja Udaykumar
pp. 63–68 · DOI: 10.4103/jpp.JPP_27_19 · Published 2019
Aim: To identify and evaluate the potential drug–drug interactions (PDDI) in hospitalized patients in a pediatric intensive care unit (PICU). Materials and Methods: In this cross‑sectional observational study, we analyze…
- Article
Application of a New “Pharmvigill©” App for the Analysis of Dermatological Adverse Drug Reaction in a Tertiary Care Hospital
Shalini Chawla, Ankur Tiwari, Shariq Naeem Syed
pp. 69–74 · DOI: 10.4103/jpp.JPP_105_18 · Published 2019
Aim: To assess the patterns of dermatological adverse drug reactions (ADRs) and drugs responsible to formulate a strategy for prevention and treatment using a new app. Materials and Methods: In the present study, 870 pat…
Case Report
- Article
Presumed Antihistamine-Induced Cataract in Two Young Males
Md. Shahid Alam, Ashwin Cherusheril Somarajan
pp. 75–6 · DOI: 10.4103/jpp.JPP_31_19 · Published 2019
The use of systemic and topical steroids, amiodarone, and phenothiazines has been established as risk factors for the development of cataract. Antihistaminics are commonly prescribed drugs for a wide range of allergic di…