Volume 10, Issue 3

Research Paper

1. Article

   Impact of Gender Variation on Calculated Plasma Concentration of Propofol (Cp50calc) to Prevent Movement Response to Surgical Stimulus in South Indian Population: A Comparative Study

   Sudar Codi Ramarajan, M. Ravishankar, K. Manimekalai, Sameera Jahagirdhar

   pp. 100–104 · DOI: 10.4103/jpp.JPP_48_19 · Published 2019

   Objective: To find out the gender differences in Cp50calc of propofol required to prevent movement response to surgical stimulus in South Indian population. Materials and Methods: A comparative study was performed on six…

2. Article

   Determination of Thiopurine S‑methyltransferase Activity using Reverse‑Phase High‑Performance Liquid Chromatography Assay with Ultraviolet Detection: Reference Values for the Indian Population

   Ratna Prabha, Sumith K. Mathew, A. J. Joseph, Binu Susan Mathew

   pp. 105–110 · DOI: 10.4103/jpp.JPP_65_19 · Published 2019

   Objective: To determine thiopurine S‑methyltransferase (TPMT) activity and the range of TPMT activity values for the Indian population. Methods: An isocratic reversed‑phase high‑performance liquid chromatography method w…

3. Article

   Comparison of Adherence to ARRIVE Guidelines in Animal Research Articles Published in the Years 2009 and 2016 in Pharmacology Journals: An Observational Study

   Sharmila Jalgaonkar, Tausif Mapara, Apoorv Verma, Mohsin Sayyed

   pp. 77–84 · DOI: 10.4103/jpp.JPP_56_19 · Published 19 November 2019

   Objective: To evaluate and compare the adherence of the ARRIVE guidelines before and after its introduction by the articles published by two leading journals publishing animal research articles. Materials and Methods: Li…

4. Article

   Curcumin Recovers the Toxic Effects of Nicotine on Hippocampus Cornu Ammonis 1 in Rats

   Mohammad Reza Salahshoor, Amir Abdolmaleki, Shiva Roshankhah, Amir Jalali, Cyrus Jalili

   pp. 85–92 · DOI: 10.4103/jpp.JPP_38_19 · Published 2019

   Objective: To evaluate the effects of curcumin (CUM) against Nicotine (NIC) induced damage to the hippocampal cortex of rats. Materials and Methods: In this study, 48 Wistar male rats were randomly assigned to eight grou…

5. Article

   Effect of Calcium Channel Blockers on the Seizures, Oxidative Stress, and Histoarchitecture in the Rats

   K. Saniya, B. G. Patil, C. Madhavrao, K. G. Prakash

   pp. 93–99 · DOI: 10.4103/jpp.JPP_68_19 · Published 2019

   Objective: To evaluate the anticonvulsant and antioxidant actions of diltiazem, nimodipine, and flunarizine in the Wistar albino rats using the maximum electroshock‑induced seizure (MES) model. Materials and Methods: Thi…