Volume 11, Issue 4

Adaptive Designs in Clinical Trials

Sougata Sarkar, Vartika Srivastava, Chaitali Patanayak

pp. 129–133 · DOI: 10.4103/jpp.JPP_79_20 · Published 14 May 2021

The traditional clinical trial is a rigid channel of drug development process. After successful Phase 1 trials and Phase 2 trial with sufficient efficacy and safety, the drugs goes into Phase 3 trials, where it is compar…

Comparison of Topical Ivermectin and Oral Ivermectin in the Treatment of Human Scabies: A Randomized Controlled Trial

Swetabh Verma, Marya Ahsan

pp. 134–139 · DOI: 10.4103/jpp.JPP_116_20 · Published 14 May 2021

Objective: To compare the topical and oral ivermectin (IVM) in the management of scabies. Materials and Methods: An open-labeled parallel randomized trial was conducted among patients of scabies. Group A (n = 51) receive…

Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia

Anuhya Vinayaka, Shubha Sheshadri, Sharath P. Madhyastha, Ganesh V. Shetty, Charan Thej Reddy

pp. 140–141 · DOI: 10.4103/jpp.JPP_29_20 · Published 14 May 2021

Treatment of schizophrenia has taken so many turns, and adverse effects of the drugs still continue to remain as a hurdle in the management. Clozapine is considered to be the better promising drug in the treatment of par…

Scenarios in Medical Ethics-1: Composition and Functioning of Ethics Committees

Harivenkatesh Natarajan, Jayanthi Mathaiyan, Raveendran Ramasamy

pp. 142–144 · DOI: 10.4103/jpp.jpp_171_20 · Published 2020

A bioethics training workshop for Institutional Ethics Committee (IEC) members was organized on 16th–17th September 2019 at Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry in South India i…

Scenarios in Medical Ethics 2: Challenges for Ethics Committees

Jayanthi Mathaiyan, Harivenkatesh Natarajan, Narayanan Parameswaran, C. Suthakaran

pp. 145–147 · DOI: 10.4103/jpp.jpp_172_20 · Published 14 May 2021

A series of panel discussions were conducted as part of the 2-day workshop on medical research ethics, organized for Ethics committee (EC) members at the Jawaharlal Institute of Postgraduate Medical Education and Researc…

Scenarios in Medical Ethics-3: New Drugs and Clinical Trials Rules 2019

Jayanthi Mathaiyan, Prasanth Ganesan, Tamilarasu Kadhiravan, Nishanthi Anandabaskar

pp. 148–150 · DOI: 10.4103/jpp.jpp_173_20 · Published 2020

Scenarios in Medical Ethics-4: Ethics Committee-Registration and Accreditation

Medha Rajappa, Jayanthi Mathaiyan, Rajendran Priyadharsini

pp. 151–153 · DOI: 10.4103/jpp.jpp_174_20 · Published 14 May 2021

It is mandatory for all ethics committees in India reviewing biomedical and health research studies to register with the Department of Health Research (DHR) under the Ministry of Health and Family Welfare. This informati…

Scenarios in Medical Ethics-5: Informed Consent Process

Jayanthi Mathaiyan, Narayanan Parameswaran, Harivenkatesh Natarajan, R. Raveendran

pp. 154–156 · DOI: 10.4103/jpp.jpp_175_20 · Published 14 May 2021

Informed consent process is becoming more challenging these days with researchers involved in collecting data during complex situations like an emergency or an epidemic. Other concerns are about translating into local la…

Scenarios in Medical Ethics-6: Public Health Research

Subitha Lakshminarayanan, S. Sandhiya, Jayanthi Mathaiyan, Reba Kanungo

pp. 157–159 · DOI: 10.4103/jpp.jpp_176_20 · Published 14 May 2021

Indian Council of Medical Research (ICMR) ethical guidelines 2017 had for the first time introduced the chapter on public health research, which is a replacement of the chapter on epidemiology in the previous version. In…