Volume 11, Issue 3

Targeting Oxidative Stress, Transforming Growth Factor Beta-1, and the Mammalian Target of Rapamycin by Valproic Acid to Ameliorate Bleomycin-Induced Scleroderma

Maaly A. Abd Elmaaboud, Mohamed S. Omar, Ahmed M. Kabel

pp. 100–106 · DOI: 10.4103/jpp.JPP_99_20 · Published 23 December 2020

Objective: To explore the possible ameliorative effect of valproic acid on the experimental model of skin fibrosis induced by bleomycin. Materials and Methods: Forty male BALB/c mice were divided into four equal groups a…

Magnesium Sulfate versus Clonidine As an Adjuvant to Ultrasound-Guided Supraclavicular Brachial Plexus Block in Upper Limb Surgery: A Double-Blind Randomized Controlled Trial

Archana Mohanakumar, Ramyavel Thangavelu, Anju Annie Paul, R. V. Ranjan, Sagiev Koshy George

pp. 107–112 · DOI: 10.4103/jpp.JPP_98_20 · Published 23 December 2020

Objective: To compare the efficacy of clonidine and magnesium sulfate (MgSO4) when administered as an adjuvant to supraclavicular brachial plexus block in upper limb surgery. Materials and Methods: Sixty patients belongi…

Effect of Oral Isotretinoin on Anxiety and Depression in Patients with Acne

Balkrisha Nikam, Varsha Jamale, S. Tapdia Ravikumar

pp. 113–118 · DOI: 10.4103/jpp.JPP_17_20 · Published 23 December 2020

Objective: To study the side effect profile of systemic isotretinoin (ITT) and its association with anxiety and depression in the Indian population. Materials and Methods: In this prospective observational study, 300 pat…

Uropathogens Causing Urinary Tract Infection in Adults in a Tertiary Care Hospital

R. Abisha Rezia, R. Vijendra, Anjana Gopi

pp. 119–124 · DOI: 10.4103/jpp.JPP_100_20 · Published 2020

Objective: To study the profile of uropathogens, causing UTI in adults in our hospital and research center, assess their pattern of antimicrobial susceptibility, the clinical course, and outcome. Materials and Methods: T…

Assessment of Utilization and Rationality of Analgesic Drugs in Perioperative Setting in a Tertiary Care Teaching Institute

Nirmik Dongre, Sujata Dudhgaonkar, Kavita M Jaiswal, Nandkishore Jaiswal, Lohit S. Vaishnao

pp. 125–126 · DOI: 10.4103/jpp.JPP_71_20 · Published 23 December 2020

Erratum: Curcumin Improves the Behavior and Memory in Mice by Modulating the Core Circadian Genes and Their Associated Micro-RNAs

pp. 127–127 · DOI: 10.4103/0976-500X.300357 · Published 2020

Warfarin: Looking Beyond Vitamin K in Diet

Navneet Attri, Lenora Farnam-Fard

pp. 87–89 · DOI: 10.4103/jpp.JPP_102_20 · Published 23 December 2020

Warfarin has been widely used for its anticoagulant properties. It has a narrow therapeutic range with complex interactions with various dietary products, herbal supplements, and with other medications. We recently encou…

Current Medicines for Malaria Including Resistance Issues

Dejen Nureye, Mohammed Salahaddin, Ameha Zewudie

pp. 90–99 · DOI: 10.4103/jpp.JPP_23_20 · Published 23 December 2020

Malaria is an old disease and continues to be a major health problem in many countries. In spite of decrement in morbidity and mortality due to malaria, the transmission is still active throughout the world. Hence, appro…