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    Journal of Pharmacology and Pharmacotherapeutics volume 14, issue 1 cover
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    Cover: Journal of Pharmacology and Pharmacotherapeutics

    Journal of Pharmacology and Pharmacotherapeutics

    Volume 14, Issue 1

    2023 · pp. 5–87 · 11 articles

    Volume
    14
    Issue
    1
    Published
    2023
    Pages
    5–87
    Articles
    11
    Sections
    3
    ISSN
    ISSN: Print - 0976-500X, Online - 0976-5018
    Journal
    J Pharmacol. Pharmacother.

    In this issue

    Review Article

    1. Review

      Probiotics: A Review on Microbiome That Helps for Better Health – A Dermatologist’s Perspective

      Sane Roja Renuka, N. Ashok Kumar, D. Manoharan, Dama Kondaiah Naidu

      pp. 5–13 · DOI: 10.1177/0976500X231175225 · Published 2023

      Commensal microorganisms heavily influence human health and disease pathogenesis, and the impact of the skin microbiome on numerous skin illnesses has recently piqued researchers’ interest, in addition to the gut microbi…

    2. Review

      Food-derived Bioactive Peptides with Angiotensin-Converting Enzyme Inhibiting Effect: A Systematic Review

      Albeiro Marrugo Padilla, Johana Márquez Lázaro

      pp. 14–24 · DOI: 10.1177/0976500X231175217 · Published 2023

      Objective: To describe the current scientific evidence of food-derived bioactive peptides and their angiotensin-converting enzyme inhibiting effect. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Anal…

    Research Article

    1. Article

      Evaluation of Virtual Reality High-Fidelity Adult Mannequin-based Simulation of Real-Life Clinical Scenarios in Teaching Clinical Pharmacology to Medical Students

      Anupama M. Gudadappanavar, Prashant Hombal, Jyoti M. Benni, Sachin Patel, Basavaraj R. Tubaki

      pp. 25–34 · DOI: 10.1177/0976500X231159456 · Published 2023

      Background: Presently, competency-based medical (CBME) curriculum challenges the medical educators to provide continuing education with new approaches to make learning more stimulating, motivating, and entertaining, fost…

    2. Article

      Incidence, Patterns, and Severity of Potential Drug Interactions Among Cancer Patients on Chemotherapy in a Tertiary Care Hospital

      Anuradha H.V., Vinayak V. Maka, Prakash Patil, Anupama C.

      pp. 35–40 · DOI: 10.1177/0976500X231162712 · Published 2023

      Objective: To study the incidence of potential drug−drug interactions (DDIs) and evaluate their pattern and severity in cancer inpatients. Materials and Methods: A detailed clinical data and prescriptions of 150 inpatien…

    3. Article

      Critical Evaluation of Drug Promotional Literature Using WHO Ethical Criteria and Perception of Clinicians at a Tertiary Care Hospital

      Amanjot Kaur, Shweta Singla, Mandeep Kaur, Jasninder Singh

      pp. 41–46 · DOI: 10.1177/0976500X231164812 · Published 2023

      Objective: To evaluate the rationality of drug promotional literature (DPL) using World Health Organization (WHO) ethical criteria and to evaluate the perception of clinicians regarding DPLs using prevalidated criteria. …

    4. Article

      An Observational Study on the Intraoperative Awareness Following General Anesthetic Drugs

      Nikita Haldar, Krishna Prasad T., Mali Kalpana Ramanna, Maduram Annamalai, Soundarya Priyadharsini K.

      pp. 47–53 · DOI: 10.1177/0976500X231172579 · Published 2023

      Objective: To determine intraoperative awareness and estimate the factors associated with intraoperative awareness. Methods: An observational cross-sectional study was carried out after approval from the institutional et…

    5. Article

      Selective Partial Agonism of Vasopressin 1a Receptors In Vitro by OCE-205

      Glenn Croston, Edward E. Cable, Jeannine Toy, Hiroe Tariga, Regent Laporte, Geoff Harris, Stan Bukofzer

      pp. 54–61 · DOI: 10.1177/0976500X231175220 · Published 2023

      Objective: To test the selectivity and degree of functional agonism of Ocelot Bio’s dual agonist/antagonist molecule, OCE-205, at the vasopressin 1a receptor (V1aR). Methods: Cells expressing human (h) or rat V1a, V1b, V…

    6. Article

      Influence of miR-142-3p on Pulmonary Fibrosis Through Regulation of p53/NF-κB

      Ye Shen, Heng-Jie Li, Ke Zhang, Sheng-Qin Li, Ying-Ge Xu

      pp. 62–71 · DOI: 10.1177/0976500X231175222 · Published 2023

      Objectives: To investigate the role of miR-142-3p in the bleomycin-induced idiopathic pulmonary fibrosis (IPF) mouse model and elucidate its targets. Methods: In vitro model: Alveolar epithelial cells (AECs) were isolate…

    7. Article

      Use of Fixed-dose Combination Therapy with Remogliflozin and Vildagliptin as an Add-on Drug in Improving the Glycemic Control of Type 2 Diabetes Mellitus: An Observational Study

      Velammal Petchiappan, Elsa Mathew, Josna Jose, Mohamed Fardan, Yoganathan Chidambaram, Saravanan Thangavelu

      pp. 72–78 · DOI: 10.1177/0976500X231175219 · Published 2023

      Objective: To evaluate whether a fixed dose combination (FDC) with remogliflozin and vildagliptin as an add-on therapy can improve the glycemic control in the management of type 2 diabetes mellitus and also the non-glyce…

    8. Article

      Effect of Bezafibrate, a PPARα Activator, on Acute and Subacute Inflammation in Male Wistar Rats

      Serah Johny, S. S. Torgal

      pp. 79–83 · DOI: 10.1177/0976500X231175218 · Published 2023

      Aim: To investigate the anti-inflammatory effect of bezafibrate on acute and subacute inflammation in adult male Wistar rats. Methods: The study was carried out in adult male Wistar rats and they were allocated into thre…

    Case Report

    1. Article

      Challenges in Anesthetic Management of Succinylcholine-induced Masseter Muscle Rigidity in Difficult Airway Patient: A Case Report

      Monika Sharma, Aruna Chandak, Priyanka Dev, Aditi Prafulshatalwar

      pp. 84–87 · DOI: 10.1177/0976500X231169104 · Published 2023

      The difficult airway is already a challenging situation for anesthesiologists, in that scenario Succinylcholine (SCh) use, because of its rapid onset and short duration of action makes it a neuromuscular blockage drug of…