Volume 14, Issue 3

A Glimpse into the Diverse Horizons of Pharmacological Research: Insights From the Latest Issue

Mueen Ahmed

pp. 169–170 · DOI: 10.1177/0976500X231221181 · Published 2023

Perspectives of ChatGPT in Pharmacology Education, and Research in Health Care: A Narrative Review

Chetna R. Patel, Sajal K. Pandya, Brijesh M. Sojitra

pp. 171–177 · DOI: 10.1177/0976500X231210427 · Published 2023

In the era of advanced Open artificial intelligence (AI) technology, the large language model tool known as chat generative pre-training transformer (ChatGPT) is gaining an increasing number of users in various fields su…

Various Factors Influencing the Enantiomers of Warfarin Pharmacokinetics: A Systematic Review of Population Pharmacokinetics

Sirajudeen Mahaboob, G.N.K. Ganesh, K.P. Arun, S.D. Rajendran

pp. 178–186 · DOI: 10.1177/0976500X231211401 · Published 2023

Warfarin is the most commonly prescribed anti-coagulant medication. Warfarin’s pharmacokinetics (PK) in its enantiomeric form have been reported to be highly variable. Five population pharmacokinetic model studies for wa…

Moringa oleifera Modulates MPTP-induced Mitochondrial Dysfunction in Parkinson’s Mouse Model: An in silico and in vivo Analysis

Smriti Singh, Priyanka Kumari Keshri, Vijaya Nath Mishra, Surya Pratap Singh

pp. 187–200 · DOI: 10.1177/0976500X231220085 · Published 2023

Background: Parkinson’s disease (PD) is a movement-affecting neurodegenerative condition with an unclear etiology. Recent research suggests targeting poly-(adenosine 5-diphosphate-ribose) polymerase 1 (PARP1) as a potent…

A Study to Evaluate the Efficacy of Saroglitazar in Non-Alcoholic Steatohepatitis Induced by High Fructose Diet Rat Model

Saravanan T., Shanmugapriya S., Eliz Thomas, Karthika P.

pp. 201–209 · DOI: 10.1177/0976500X231213486 · Published 2023

Background: Non-alcoholic steatohepatitis (NASH) is a clinical condition with a global prevalence of 25.24%. Peroxisome proliferator-activated receptors (PPAR) have been significantly associated with the pathogenesis of …

Anti-rheumatic and Memory-enhancing Effect of Memantine on Complete Freund’s Adjuvant-induced Rheumatoid Arthritis Compared to Methotrexate in Wistar Rats

Sharmila V. Jalgaonkar, Sumith Ourasang, Raakhi K. Tripathi, Pradeep Vaideeswar, Padma Badhe

pp. 210–219 · DOI: 10.1177/0976500X231211394 · Published 2023

Objectives: To evaluate the anti-inflammatory and memory-enhancing effects of memantine (MEM) in complete Freund’s adjuvant (CFA)-induced rheumatoid arthritis (RA) in Wistar rats. The effect of MEM on cognition in CFA-in…

Cost-effectiveness and Side Effects of Using Heparin and Enoxaparin as a Treatment for COVID-19-associated Coagulopathy

Nurul Iska Ulmarika Idris, Abdul Khairul Rizki Purba, Arifa Mustika, Anna Surgean Veterini, Mochamad Yusuf Alsagaff, Mohammad Qorib

pp. 220–230 · DOI: 10.1177/0976500X231217140 · Published 2023

Objective: To analyze the cost-effectiveness and side effects of Heparin and Enoxaparin anti-coagulant in patients with COVID-19-associated coagulopathy (CAC). Materials and Methods: This was an observational study with …

Effect of Fluoxetine and Escitalopram on Heart Rate Variability (HRV) and Serum Potassium Level in Patients of Depression and Anxiety Disorders

Truptiben R Machhi, Chetna R. Patel, Sajal K. Pandya, N. D. Kantharia

pp. 231–237 · DOI: 10.1177/0976500X231213153 · Published 2023

Background: The present study was conducted to generate data regarding the effect of fluoxetine as an anti-depressant and escitalopram as an antianxiety agent on heart rate variability (HRV). There is a scarcity of data …

Aristolochia bracteolata Lam.’s Toxicity Profile and Neuroprotective Effects in Mice with Memory Impairment Triggered by Scopolamine

Dhivya P. Sundaram, Swathy Govindaswamy, Sridevi Sangeetha K. S., Palanisamy Selvamani, Subbiah Latha

pp. 238–245 · DOI: 10.1177/0976500X231215933 · Published 2023

Aim: The present study aims to investigate the toxicity profile and neuroprotective effect of ethanol crude extract of Aristolochia bracteolata (EEAB) leaves in mice. Materials and Methods: EEAB was subjected to prelimin…

Terbinafine-induced Myositis: A Case Report

Atiqulla Shariff, Vaishakhi Shetty, Muskan Singh, Anjani Kumari, Sathvik Belagodu Sridhar, Srikanth Malavalli Siddalingegowda

pp. 246–248 · DOI: 10.1177/0976500X231214031 · Published 2023

We report a case of terbinafine-induced myositis in a 37-year-old Asian male patient treated for Tinea cruris. The patient complained of severe generalized body aches, weakness, fever, fatigue, and passing of concentrate…