Isolation of forskolin from stem of Coleus forskohlii
A.M. Saleem1,2★, P.B. Dhasan3, M.R.M. Rafiullah4★ Corresponding author
- 1Department of Pharmacognosy, C.L.Baid Metha College of Pharmacy, Thoraippakkam, Chennai 600096, India.
- 2School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan R.O.C.
- 3Department of Siddha Medicine, Tamil University, Thanjavur 613500, India.
- 4Faculty of Pharmacy, Hamdard University, New Delhi 110062, India.
CORRESPONDENCE
A.M. Saleem
Department of Pharmacognosy, C.L.Baid Metha College of Pharmacy, Thoraippakkam, Chennai 600096, India.
Volume 1, Issue 3 · pp. 89–90 · PUBLISHED 2005 · DOI:
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ABSTRACT
Forskolin was isolated from the stem of Coleus forskohlii. Chloroform extract of the powdered stem was subjected to silica gel column chromatography to obtain crude forskolin. The crude forskolin was crystallized using ethyl acetate and n-hexane to obtain pure forskolin. The forskolin isolated was characterized by using UV, IR, ESI-Mass, 1H and 13C NMR. The yield was 0.103% w/w based on the dry weight of stem powder. The present study reconfirmed existing data on physical and spectroscopic characterization of forskolin.
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Saleem, A., Dhasan, P., & Rafiullah, M. (2005). Isolation of forskolin from stem of Coleus forskohlii. Pharmacognosy Magazine, 1(3), 89–90.