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    Optimization of ultrasonic‑assisted extraction of antioxidant compounds from Guava (Psidium guajava L.) leaves using response surface methodology

    Fansheng Kong2,3,4, Shujuan Yu2,4, Zeng Feng2, Xinlan Wu2 Corresponding author

    1. 1College of Light Industry and Food Sciences, South China University of Technology, China.
    2. 2Department of Pharmaceutical Engineering, College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
    3. 3Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, Guangzhou 510640, PR, China.

    CORRESPONDENCE

    Shujuan Yu

    Department of Pharmaceutical Engineering, College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.

    shujuanyu8@gmail.com

    Received: 02-08-2014; Revised: 17-08-2014.

    Volume 11, Issue 43 · pp. 463–469 · PUBLISHED 10 July 2015 · DOI: 10.4103/0973-1296.160451

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Objective: To optimization of extraction of antioxidant compounds from guava (Psidium guajava L.) leaves and showed that the guava leaves are the potential source of antioxidant compounds. Materials and Methods: The bioactive polysaccharide compounds of guava leaves (P. guajava L.) were obtained using ultrasonic‑assisted extraction. Extraction was carried out according to Box‑Behnken central composite design, and independent variables were temperature (20–60°C), time (20–40 min) and power (200–350 W). The extraction process was optimized by using response surface methodology for the highest crude extraction yield of bioactive polysaccharide compounds. Results: The optimal conditions were identified as 55°C, 30 min, and 240 W. 1,1‑diphenyl‑2‑picryl‑hydrazyl and hydroxyl free radical scavenging were conducted. Conclusion: The results of quantification showed that the guava leaves are the potential source of antioxidant compounds.

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      Kong, F., Yu, S., Feng, Z., & Wu, X. (2015). Optimization of ultrasonic‑assisted extraction of antioxidant compounds from Guava (Psidium guajava L.) leaves using response surface methodology. Pharmacognosy Magazine, 11(43), 463–469. https://doi.org/10.4103/0973-1296.160451