Volume 11, Issue 43

2026-09-10 · pp. · 31 articles

Volume: 11
Issue: 43
Published: 2026-09-10
Pages
Articles: 31
Sections: 2
ISSN: ISSN: Print - 0973-1296, Online - 0976-4062
Journal: Pharmacogn. Mag.

Original Article ORIGINAL ARTICLE

In this issue

Original Article

Article
Three statistical experimental designs for enhancing yield of active compounds from herbal medicines and anti‑motion sickness bioactivity
Yan Chen, Cuiping Zhang, Mei Zhang, Xiaobing Fu
pp. 435–443 · DOI: 10.4103/0973-1296.160444 · Published 10 July 2015
Background: Since antiquity, Zingiber officinale (ginger), pogostemonis herba, and radix aucklandiae have been used as traditional Chinese medicines to remit gastrointestinal discomfort. Recent evidences also show the ef…
Article
Purification and characterization of an anticoagulant oligopeptide from Whitmania pigra Whitman
Xiaobei Zheng, Juan Li, Zhengwang Chen, Yimei Liu, Keli Chen
pp. 444–448 · DOI: 10.4103/0973-1296.160446 · Published 10 July 2015
Background: Dried Whitmania pigra is used for the treatment of cardiovascular and cerebrovascular diseases in traditional Chinese medicine and hot water and alcohol extracts also have anticogulant activity. However, a lo…
Article
Anti‑aging effect of polysaccharide from Bletilla striata on nematode Caenorhabditis elegans
Yusi Zhang, Ting Lv, Min Li, Ting Xue, Hui Liu, Weiming Zhang, Xiaoyu Ding, Ziheng Zhuang
pp. 449–454 · DOI: 10.4103/0973-1296.160447 · Published 10 July 2015
Background: Polysaccharide isolated from Bletilla striata, a well‑known traditional Chinese medicine (Bletilla striata polysaccharide [BSP]) has been found to play important roles in endothelial cells proliferation, indu…
Article
A study of pharmacokinetic interactions among co‑existing ingredients in Viscum coloratum after intravenous administration of three different preparations to rats
Yuying Ma, Ronghua Fan, Mengmeng Duan, Zhiguo Yu, Yunli Zhao
pp. 455–462 · DOI: 10.4103/0973-1296.160448 · Published 10 July 2015
Background: Viscum coloratum (Komar) Nakai, known as Hujisheng in china, has been widely used as a herb medicine to treat a variety of diseases, including cardiovascular diseases, cancer, hypertension, hepatitis and hemo…
Article
Optimization of ultrasonic‑assisted extraction of antioxidant compounds from Guava (Psidium guajava L.) leaves using response surface methodology
Fansheng Kong, Shujuan Yu, Zeng Feng, Xinlan Wu
pp. 463–469 · DOI: 10.4103/0973-1296.160451 · Published 10 July 2015
Objective: To optimization of extraction of antioxidant compounds from guava (Psidium guajava L.) leaves and showed that the guava leaves are the potential source of antioxidant compounds. Materials and Methods: The bioa…
Article
Selective and cost‑effective protocol to separate bioactive triterpene acids from plant matrices using alkalinized ethanol: Application to leaves of Myrtaceae species
Adélia M. Belem Lima, Antonio Carlos Siani, Marcos Jun Nakamura, Luiz Antonio D’Avila
pp. 470–476 · DOI: 10.4103/0973-1296.160453 · Published 10 July 2015
Background: Triterpenes as betulinic (BA), oleanolic (OA) and ursolic acids (UA) have increasingly gained therapeutic relevance due to their wide scope of pharmacological activities. To fit large‑scale demands, exploitab…
Article
A direct protein kinase B‑targeted anti‑inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris
Ju Young Yoon, Ji Hye Kim, Kwang‑Soo Baek, Geum Soog Kim, Seung Eun Lee, Dae Young Lee, Je Hun Choi, Seung Yu Kim, Hyun Bong Park, Gi‑Ho Sung, Kang Ro Lee, Jae Youl Cho, Hyung Jun Noh
pp. 477–485 · DOI: 10.4103/0973-1296.160454 · Published 10 July 2015
Background: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities. Objective: The objective of the following study is to isolate chem…
Article
Traditional medicine yanggyuksanhwa‑tang inhibits adipogenesis and suppresses proliferator‑activated receptor‑gamma expression in 3T3‑L1 cells
Soo‑Jin Jeong, Sae‑Rom Yoo, Chang‑Seob Seo, Hyeun‑Kyoo Shin
pp. 502–508 · DOI: 10.4103/0973-1296.160456 · Published 10 July 2015
Background: Yanggyuksanhwa‑tang (YGSHT) is a specific traditional Korean herbal formula for Soyangin according to Sasang constitutional philosophy. Although its biological activities against inflammation and cerebral inf…
Article
Region‑selective biosynthesis of artemisinic acid glycosides by crown galls of Panax quinquefolium and their in vitro antitumor activities
Jianhua Zhu, Lijia Chen, Xianjing Hu, Liyan Song, Mingxuan Wang, Rongmin Yu
pp. 518–523 · DOI: 10.4103/0973-1296.160460 · Published 10 July 2015
Background: The biosynthesis of artemisinin derivatives is one of the interesting subjects. Artemisinic acid (AA) has been widely studied as a supposed intermediate in the biosynthetic pathway leading to artemisinin in A…
Article
Protective effect of calycosin‑7‑O‑β‑D‑glucopyranosi de against oxidative stress of BRL‑3A cells induced by thioacetamide
Li Jian, Lin Xin, Ma Yufang, Huang Yifan
pp. 524–532 · DOI: 10.4103/0973-1296.160461 · Published 10 July 2015
Background: Calycosin‑7‑O‑β‑D‑glucopyranoside (CG) is a natural isoflavone found in traditional Chinese medicines Astragali Radix (AR). Objective: Calycosin‑7‑O‑β‑D‑glucopyranoside, an isoflavone isolated from AR, has be…
Article
The ethanolic extract of Juglans sinensis leaves and twigs attenuates CCl4‑induced hepatic oxidative stress in rats
Heejung Yang, Sang Hyun Sung, Young Choong Kim
pp. 533–539 · DOI: 10.4103/0973-1296.160463 · Published 10 July 2015
Background: The nuts of Juglans sinensis Dode, walnut tree, are rich in unsaturated fatty acids and bioactive compounds with antioxidant activity on liver damages. However, hepatoprotective activity of the leaves and twi…
Article
Simultaneous quantification of crocetin esters and picrocrocin changes in Chinese saffron by high‑performance liquid chromatography‑diode array detector during 15 years of storage
Yingpeng Tong, Yongqiu Yan, Xingyi Zhu, Ruoxi Liu, Feng Gong, Ling Zhang, Ping Wang
pp. 540–545 · DOI: 10.4103/0973-1296.160467 · Published 10 July 2015
Background: Saffron, which is made up of the dried stigmas of Crocus sativus L., has been successfully cultivated in China since 1970s and Zhejiang province is now the largest producing area in China, but the contents of…
Article
Microwave‑assisted extraction of polysaccharides from Yupingfeng powder and their antioxidant activity
Dan Wang, Bi‑Bo Zhang, Xiao‑Xia Qu, Feng Gao, Min‑Yong Yuan
pp. 546–554 · DOI: 10.4103/0973-1296.160468 · Published 10 July 2015
Background: Microwave‑assisted reflux extraction of polysaccharides YPF-P from the famous Chinese traditional drug, Yupingfeng powder, optimization of extracting conditions and evaluation of their antioxidant activity we…
Article
Simultaneous determination of nine marker compounds in the traditional Korean medicine, Dangguisu‑san by high‑performance liquid chromatography
Chang‑Seob Seo, Hyeun‑Kyoo Shin
pp. 555–561 · DOI: 10.4103/0973-1296.160457 · Published 10 July 2015
Background: Dangguisu-san (DGSS) has been widely used to treat ecchymosis, blood stagnation and pain resulting from physical shock in Korea. Objective: A high‑performance liquid chromatography– photodiode array detection…
Article
Simultaneous determination of three sesquiterpene lactones in Aucklandia lappa Decne by high‑performance liquid chromatography
Chang‑Seob Seo, Hyeun‑Kyoo Shin
pp. 562–566 · DOI: 10.4103/0973-1296.160471 · Published 10 July 2015
Background: Aucklandia lappa Decne, a well‑known traditional herbal medicine, is used for the treatment of asthma, rheumatism, coughs, tuberculosis, and many other diseases. Objective: We performed simultaneous analysis …
Article
Total saponins from Discorea nipponica makino ameliorate urate excretion in hyperuricemic rats
Qi Zhou, Dong-Hua Yu, Shu-Min Liu, Ying Liu
pp. 567–573 · DOI: 10.4103/0973-1296.160442 · Published 10 July 2015
Objective: The objective was to study the mechanism of reducing level of the uric acid by rhizoma dioscoreae nipponese. Materials and Methods: A total of 40 rats were divided into four groups: A normal group, hyperuricem…
Article
Optimization of induction, subculture conditions, and growth kinetics of Angelica sinensis (Oliv.) Diels callus
Bing Huang, Lijuan Han, Shaomei Li, Chunyan Yan
pp. 574–578 · DOI: 10.4103/0973-1296.160443 · Published 10 July 2015
Background: Angelica sinensis (Oliv.) Diels is an important traditional Chinese medicine, and the medicinal position is its root. This perennial herb grows vigorously only in specific areas and the environment. Tissue cu…
Article
Neuroprotective activity of parawixin 10, a compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae) in rats undergoing intrahippocampal NMDA microinjection
Helene Aparecida Fachim, Marcia Renata Mortari, Leonardo Gobbo‑Netto, Wagner Ferreira dos Santos
pp. 579–585 · DOI: 10.4103/0973-1296.160450 · Published 10 July 2015
Background: Parawixia bistriata is a semi‑colonial spider found mainly in southeastern of Brazil. Parawixin 10 (Pwx 10) a compound isolated from this spider venom has been demonstrated to act as neuroprotective in models…
Article
Metabolic fingerprinting to understand therapeutic effects and mechanisms of silybin on acute liver damage in rat
Qun Liang, Cong Wang, Binbing Li, Ai‑hua Zhang
pp. 586–593 · DOI: 10.4103/0973-1296.160469 · Published 10 July 2015
Background: Metabolic fingerprinting is a rapid and noninvasive analysis, representing a powerful approach for the characterization of phenotypes and the distinction of specific metabolic states due to environmental alte…
Article
Biological activities of Croton palanostigma Klotzsch
Eduardo Ferreira Mota, Diele Magno Rosario, Andreza Socorro Silva Veiga, Davi Do Socorro Barros Brasil, Fernando Tobias Silveira, Maria Fâni Dolabela
pp. 601–606 · DOI: 10.4103/0973-1296.160449 · Published 10 July 2015
Background: Different species of Croton are used in traditional Amazonian medicine. Among the popular uses are treatment of bacterial diseases, poorly healing wounds and fevers. Objective: This study evaluated the antile…
Article
Phytochemical screening, antioxidant and antibacterial activities of extracts prepared from different tissues of Schinus terebinthifolius Raddi that occurs in the coast of Bahia, Brazil
Cinara Oliveira D’Sousa’ Costa, Paulo Roberto Ribeiro, Marta Bruno Loureiro, Rafael Conceição Simões
pp. 607–614 · DOI: 10.4103/0973-1296.160459 · Published 10 July 2015
Background: Schinus terebinthifolius is widely used in traditional medicine by Brazilian quilombola and indigenous communities for treatment of several diseases. Extracts from different tissues are being used to produce …
Article
Chemical constituents and antioxidant activity of the essential oil from leaves of Annona vepretorum Mart. (Annonaceae)
Camila de Souza Araújo, Ana Paula de Oliveira, Rafaely Nascimento Lima, Péricles Barreto Alves
pp. 615–618 · DOI: 10.4103/0973-1296.160462 · Published 10 July 2015
Background: Annona vepretorum (AV) is a native tree from Caatinga biome (semiarid region of Brazil) popularly known as “araticum” and “pinha da Caatinga.” Objective: This study was carried out to evaluate the chemical co…
Article
A high performance liquid chromatography with ultraviolet method for Eschweilera nana leaves and their anti‑inflammatory and antioxidant activities
Priscila M. Outuki, Nides S. Lazzeri, Lizziane M. B. de Francisco, Ciomar A. Bersani‑Amado
pp. 619–626 · DOI: 10.4103/0973-1296.160464 · Published 10 July 2015
Background: Eschweilera nana Miers is a tree widely distributed in Cerrado, Brazil. Objective: In this study, we aimed to describe its phytochemical properties and antioxidant and topical anti‑inflammatory effects for th…
Article
Luteolin is a bioflavonoid that attenuates adipocyte‑derived inflammatory responses via suppression of nuclear factor‑κB/mitogen‑activated protein kinases pathway
Sarmila Nepali, Ji‑Seon Son, Barun Poudel, Ji‑Hyun Lee, Young‑Mi Lee, Dae‑Ki Kim
pp. 627–635 · DOI: 10.4103/0973-1296.160470 · Published 10 July 2015
Background: Inflammation of adipocytes has been a therapeutic target for treatment of obesity and metabolic disorders which cause insulin resistance and hence lead to type II diabetes. Luteolin is a bioflavonoid with man…
Article
In situ pressurized biphase acid hydrolysis, a promising approach to produce bioactive diosgenin from the tubers of Dioscorea Zingiberensis
Huan Yang, Hua‑wu Yin, Xue‑wei Wang, Zi‑hao Li, Yu‑ping Shen, Xiao‑bin Jia
pp. 636–642 · DOI: 10.4103/0973-1296.160472 · Published 10 July 2015
Background: The tubers of Dioscorea zingiberensis, is the most favorable plant material for the production of diosgenin, an important bioactive steroidal sapogenin and requisite precursor of cortin, contraceptive and sex…
Article
On‑line quantitative monitoring of liquid‑liquid extraction of Lonicera japonica and Artemisia annua using near‑infrared spectroscopy and chemometrics
Sha Wu, Ye Jin, Qian Liu, Qi-an Liu, Jianxiong Wu, Yu-an Bi, Zhengzhong Wang, Wei Xiao
pp. 643–650 · DOI: 10.4103/0973-1296.160465 · Published 10 July 2015
Background: Liquid‑liquid extraction of Lonicera japonica and Artemisia annua (JQ) plays a significant role in manufacturing Reduning injection. Many process parameters may influence liquid‑liquid extraction and cause fl…
Article
Flavonoids isolated from Lespedeza cuneata G. Don and their inhibitory effects on nitric oxide production in lipopolysaccharide‑stimulated BV-2 microglia cells
Guijae Yoo, Seon Ju Park, Taek Hwan Lee, Heejung Yang, Yoon‑su Baek, Nanyoung Kim
pp. 651–656 · DOI: 10.4103/0973-1296.160466 · Published 10 July 2015
Background: Lespedeza cuneata (Dum. Cours.) G. Don, a perennial legume native to Eastern Asia, has been used therapeutically in traditional Asian medicine to protect the function of liver, kidneys and lungs. However, its…
Article
Quantification of maltol in Korean ginseng (Panax ginseng) products by high‑performance liquid chromatography‑diode array detector
Hyun Cheol Jeong, Hee‑Do Hong, Young‑Chan Kim, Young Kyoung Rhee, Sang Yoon Choi, Kyung‑Tack Kim, Sung Soo Kim, Young‑Chul Lee, Chang‑Won Cho
pp. 657–664 · DOI: 10.4103/0973-1296.160452 · Published 10 July 2015
Background: Maltol, as a type of phenolic compounds, is produced by the browning reaction during the high‑temperature treatment of ginseng. Thus, maltol can be used as a marker for the quality control of various ginseng …
Article
Effect of modified Bo‑yang‑Hwan‑o‑Tang, a polyherbal medicine on the hippocampal neuronal damage in a rat model of global ischemia
Tae Woo Oh, Hyo Won Jung, Yong‑Ki Park
pp. 665–673 · DOI: 10.4103/0973-1296.160445 · Published 10 July 2015
Background: Chronic cerebral hypoperfusion has been well‑characterized as a common pathological status contributing to vascular dementia (VD). In this study, the neuroprotective effect of modified Bo‑yang‑Hwan‑O‑Tang (mB…

ORIGINAL ARTICLE

Article
Profiling of components of rhizoma et radix polygoni cuspidati by high-performance liquid chromatography with ultraviolet diode-array detector and ion trap/time-of-flight mass spectrometric detection
Jinfeng Fu, Min Wang, Huimin Guo, Yuan Tian, Zunjian Zhang, Rui Song
pp. 486–493 · DOI: 10.4103/0973-1296.160455 · Published 10 July 2015
Introduction: Rhizoma et Radix Polygoni Cuspidati (Huzhang in Chinese, HZ) is a traditional medicinal plant in China. Many of the components of HZ have been proved to be bioactive while it is difficult to conduct a compr…
Article
Simultaneous determination of four active components in rat plasma by ultra‑high performance liquid chromatography tandem‑mass spectrometry/mass spectrometry and its application to a pharmacokinetic study after oral administration of Callicarpa nudiflora extract
Jun Shao, Shuangcheng Ma, Dongkun Zheng, Weikang Chen, Yuehua Luo
pp. 509–510 · DOI: 10.4103/0973-1296.160458 · Published 10 July 2015
Background: Callicarpa nudiflora has been commonly used as a Chinese folk medicine for resolving toxin, dispersing edema and hemostasis; however, its pharmacokinetic (PK) behavior remains unknown. In our present study, a…