Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Pharmacognosy MagazineNOW IN
    Article

    Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract

    Xiaoying Chen1, Shuangshuang Qin1★, Cui Li1, Qinghua Wu1, Chao Jiang2, Jian Yang2, Xiaoyun Guo1, Chunli Ou1★ Corresponding author

    1. 1Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.
    2. 2National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

    CORRESPONDENCE

    Shuangshuang Qin

    Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.

    qin_double@126.com

    Received: 19-06-2018; Revised: 11-07-2018; Accepted: 15-11-2018.

    Volume 15, Issue 60 · pp. 18–23 · PUBLISHED 23 January 2019 · DOI: 10.4103/pm.pm_317_18

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> (CQ) is a well-known medicinal plant used in traditional medicine for bone healing. Objective: The present study was aimed to evaluate the anti-inflammatory and antioxidant activities of the methanolic extract of <em>Cissus quadrangularis</em> stem (MECQ). Materials and Methods: The anti-inflammatory activity was evaluated using the carrageenan-induced rat paw edema model. The antioxidant activity was assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay, and total phenolic content (TPC) determination. Results: MECQ showed significant anti-inflammatory activity in a dose-dependent manner. It also exhibited potent antioxidant activity with high TPC. Conclusion: The results suggest that MECQ possesses significant anti-inflammatory and antioxidant activities, which may be attributed to the presence of phenolic compounds.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Chen, X., Qin, S., Li, C., Wu, Q., Jiang, C., Yang, J., Guo, X., & Ou, C. (2019). Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract. Pharmacognosy Magazine, 15(60), 18–23. https://doi.org/10.4103/pm.pm_317_18