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    Pharmacognosy MagazineNOW IN
    Article

    Prospecting Indian Barleria Species for their Antioxidants, Anti‑Bronchial, and Anti‑Cancer Compounds

    Sandeep R. Pai1★, Parthraj R. Kshirsagar2, Nilesh V. Pawar3, Mansingraj S. Nimbalkar4★★ Corresponding author

    1. 1Department of Botany, Rayat Shikshan Sanstha’s Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, College, Shivaji Peth, Kolhapur, Maharashtra, India.
    2. 2Department of Botany, Shri Shivaji Mahavidyalaya, Barshi, Maharashtra, College, Shivaji Peth, Kolhapur, Maharashtra, India.
    3. 3Department of Botany, The New College, Shivaji Peth, Kolhapur, Maharashtra, India.
    4. 4Laboratory of Cytogenetics and Plant Breeding, Department of Botany, Shivaji University, Vidya Nagar, Kolhapur, Maharashtra, India.

    CORRESPONDENCE

    Sandeep R. Pai

    Department of Botany, Rayat Shikshan Sanstha’s Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, College, Shivaji Peth, Kolhapur, Maharashtra, India.

    drpaisr@gmail.com

    Received: 13-02-2022; Revised: 02-06-2022; Accepted: 13-08-2022.

    Volume 18, Issue 80 · pp. 886–892 · PUBLISHED 23 November 2022 · DOI: 10.4103/pm.pm_77_22

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Aim: The study herein was performed in view of prospecting 15 species and one variety of Barleria in comparison to Adathoda vasica for phytochemical composition, and antioxidant activities. Materials and Methods: In addition to this, the study also quantifies two anti‑bronchial (vasicine, vasicinone) and one anti‑cancer (betulin) compounds using reversed‑phase high‑performance liquid chromatography analysis. Results: Samples showed betulin ranging from 7.700 to 73.447 mg/g, vasicine from 0.092 to 3.710 mg/g, and vasicinone from 0.005 to 2.752 mg/g. Principal component analysis and hierarchical cluster analysis results signified the division of seventeen samples tested, into two major clades (based on a similarity range 57.83–96.60%). Conclusion: Both phytochemical analysis and antioxidant activities showed variation in the samples tested. Barleria grandiflora had higher content and better activities among the species.

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      Pai, S. R., Kshirsagar, P. R., Pawar, N. V., & Nimbalkar, M. S. (2022). Prospecting Indian Barleria Species for their Antioxidants, Anti‑Bronchial, and Anti‑Cancer Compounds. Pharmacognosy Magazine, 18(80), 886–892. https://doi.org/10.4103/pm.pm_77_22