Effects of Asiaticosides on Scar Recovery and Psychological Well-being in Patients with Scald Injuries

ABSTRACT

Background: Scar recovery in elderly burn patients is essential for wound healing and psychological well-being. Total glycosides from Centella asiatica have gained attention for their anti-inflammatory, antioxidant, and wound-healing properties, showing promise in burn care. Objectives: This study investigates the synergistic effects of combined nursing interventions and Asiaticosides on scar recovery and psychological well-being in patients undergoing scald scar repair. The pharmacological properties of these glycosides, including their anti-inflammatory, anti-oxidant, and wound-healing potential, are explored in the context of clinical care to enhance patient outcomes. Materials and Methods: A cohort of 184 patients treated for scald scars between April 2023 and April 2024 was divided into two groups: an observation group receiving combined nursing interventions with Asiaticosides, and a comparison group receiving standard care. Scar assessment was conducted using the Vancouver Scar Scale (VSS), pain was measured by the Visual Analogue Scale (VAS), and psychological states were evaluated using the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Results: Statistically significant improvements were observed in the observation group, including reduced VSS and VAS scores, as well as enhanced psychological states, compared to the control group (p < 0.05). The glycosides facilitated faster scar healing, reduced inflammation, and improved overall patient well-being. Conclusion: Asiaticosides exhibit promising therapeutic potential in enhancing scar recovery and psychological health in elderly scald patients when combined with comprehensive nursing care. Further research into their mechanisms may solidify their role in integrated scald injury management.

KEYWORDS

• Asiaticosides
• burns in the elderly
• scar repair
• mental state
• nursing intervention

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• DOI10.1177/09731296241312483Copy

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