Scanning electron microscopic observations on the in vitro anthelmintic effects of Millettia pachycarpa on Raillietina
Bishnupada Roy1, Kholhring Lalchhandama2★, Biman Kumar Dutta3★ Corresponding author
- 1Department of Zoology, North Eastern Hill University, Shillong 793 022, Meghalaya, India.
- 2Department of Zoology, Pachhunga University College, Mizoram University, Aizawl 796 001, Mizoram, India.
- 3Department of Ecology and Environmental Science, Assam University, Silchar 788 011, Assam, India.
CORRESPONDENCE
Kholhring Lalchhandama
Department of Zoology, Pachhunga University College, Mizoram University, Aizawl 796 001, Mizoram, India.
Volume 4, Issue 13 · pp. 20–21 · PUBLISHED 2008 · DOI:
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ABSTRACT
The ethanolic extract from the root bark of Millettia pachycarpa, traditionally used as a remedy for gastrointestinal infections among the Mizo tribes of north-east India, was tested in vitro to evaluate its anthelmintic activity on the poultry intestinal tapeworm, Raillietina echinobothrida. On treatment of the parasites with varying concentrations of the plant extract, viz, 0.5, 1, 2, 5, 10 and 20 mg ml-1, a dose-dependent lethal efficacy was observed. Scanning electron microscopy revealed extensive distortion and destruction on the surface fine topography of the worm. Focal truncation with formation of pits and vacuoles on the tegument were evident. Deformities on the scolex with its suckers were particularly conspicuous at the anterior extremity. The observations hereby suggest that there is credibility to the use of M. pachycarpa root bark as an anthelmintic agent.
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Roy, B., Lalchhandama, K., & Dutta, B. K. (2008). Scanning electron microscopic observations on the in vitro anthelmintic effects of Millettia pachycarpa on Raillietina. Pharmacognosy Magazine, 4(13), 20–21.