Investigation of flavonoids and antimicrobial activity of Ballota andreuzziana
Khaled Abdelshafeek1,2★, Ahmed Daboob3★ Corresponding author
- 1Altahadi University, Fac. Sci., Chem. Dept., Sirte, P.O.674, Libya.
- 2Nat. Res. Cent., Chem. of Med. Plants Dept., Dokki, Cairo, Egypt.
- 3Altahadi University, Fac. of Sci., Biology Dept., Sirte, Libya. P. O. 674, Libya.
CORRESPONDENCE
Khaled Abdelshafeek
Altahadi University, Fac. Sci., Chem. Dept., Sirte, P.O.674, Libya.
Received: 16-01-2009; Accepted: 21-06-2009.
Volume 5, Issue 19 · pp. 203–208 · PUBLISHED 2009 · DOI:
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ABSTRACT
Investigation on Ballota andreuzziana (Family Labiatae) for flavonoids led to isolation of two aglycones from ethyl acetate fraction which were identified as 7-methoxy luteolin and 6,7-dimethoxy scutellarein, in addition to three glycosides known as luteolin-7-O-glucoside, 6, 4’-dimethoxy scutellarein-7-O-glucoside and quercetin-7-O-rhamno-glucoside from butanol fraction. Antimicrobial studies revealed that, butanol extract exhibited the marked activity against M. Phlei, S. aureus and C. albicans (I.Z. =16.3, 11.3, and 10.7mm, Conc.=150mg/ml) respectively. While, chloroform extract also showed the better activity against B. subtilis (I.Z. =11.0mm, Conc.=150mg/ml). Furthermore aqueous extracts exhibited no effects at all against all tested organisms at all concentrations also, all tested Gram negative bacteria and the fungus A. niger are resistance to all concentrations of tested extracts.
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Abdelshafeek, K., & Daboob, A. (2009). Investigation of flavonoids and antimicrobial activity of Ballota andreuzziana. Pharmacognosy Magazine, 5(19), 203–208.