Antidiabetic Activity of Aqueous Extract of Eucalyptus citriodora Hook. in Alloxan Induced Diabetic Rats
Arjun Arjun1★, Shivesh Shivesh2, Alakh N N3★ Corresponding author
- 1College of Pharmacy, IFTM, Moradabad – 244 001, U.P, India.
- 2Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra – 835 215, Ranchi, Jharkhand, India.
- 3Department of Pharmaceutics, IT, BHU, Varanasi, India.
CORRESPONDENCE
Arjun Arjun
Patra Arjun,College of Pharmacy, IFTM, Moradabad – 244 001, U.P, India.
Received: 24-01-2009; Revised: 03-03-2009; Accepted: 07-06-2009.
Volume 5, Issue 19s · pp. 51–54 · PUBLISHED 2009 · DOI:
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ABSTRACT
The present study was undertaken to study the antidiabetic activity of the aqueous extract of Eucalyptus citriodora Hook. leaf in alloxan-induced diabetic rats. The activity of the extract was studied on glucose loaded and alloxan-induced diabetic rats. In both the tests, the extract has shown significant and considerable antidiabetic effect in a dose dependent manner. On oral administration of the extract at a dose of 500 mg/kg of body weight, the reduction of blood glucose level was 22.9% after 4th hr and on continuous administration the reduction in blood glucose level after 21 days was 49.9 and 56.8% with dose of 250 and 500 mg/kg of body weight respectively. Aqueous extract of leaves of E. citriodora exhibited significant antidiabetic activity which was comparable with the standard drug Glibenclamide.
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Arjun, A., Shivesh, S., & N, A. N. (2009). Antidiabetic Activity of Aqueous Extract of Eucalyptus citriodora Hook. in Alloxan Induced Diabetic Rats. Pharmacognosy Magazine, 5(19s), 51–54.