Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Pharmacognosy MagazineNOW IN
    Article

    Sterols from the red algae, Gracilaria salicornia and Hypnea flagelliformis, from Persian Gulf

    Masoumeh Nasiri1★, Soodabeh Saeidnia2, Ali Mashinchian-Moradi1, Ahmad R. Gohari2★ Corresponding author

    1. 1Department of Marine Science and Technology, Science and Research Branch, Islamic Azad University, Iran.
    2. 2Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

    CORRESPONDENCE

    Masoumeh Nasiri

    Department of Marine Science and Technology, Science and Research Branch, Islamic Azad University, Iran.

    Received: 13-07-2010; Revised: 18-09-2010.

    Volume 7, Issue 26 · pp. 97–100 · PUBLISHED 9 May 2011 · DOI: 10.4103/0973-1296.80663

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Context: Two of the important algae from Persian Gulf are Gracilaria salicornia and Hypnea flageliformis (Rhodophyta). Antibacterial, antifungal, and cytotoxic effects of the mentioned algae have been presented in the previous studies. Aim: In this study, the isolation and structural elucidation of the sterols from these algae are reported. Materials and Methods: The separation and purification of the compounds were carried out with silica gel, sephadex LH20 column chromatography (CC) and HPLC to obtain six pure compounds 1-6. The structural elucidation of the constituents was based on the data obtained from H-NMR, 13C-NMR, HMBC, HSQC, DEPT, and EI-MS. Results: The isolated compounds from G. salicornia were identified as 22-dehydrocholesterol (1), cholesterol (2), oleic acid (3), and stigmasterol (4), and the isolated constituents from H. flagelliformis were identified as 22-dehydrocholesterol (1), cholesterol (2), oleic acid (3), cholesterol oleate (5), and (22E)-cholesta-5,22-dien-3β-ol-7-one (6) based on the spectral data compared to those reported in the literature. Conclusion: Red algae are enriched with cholesterol polysaccharides. We first reported the presence of cholesteryl oleate and (22E)- cholesta-5,22-dien-3β-ol-7-one in H. flagelliformis.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Nasiri, M., Saeidnia, S., Mashinchian-Moradi, A., & Gohari, A. R. (2011). Sterols from the red algae, Gracilaria salicornia and Hypnea flagelliformis, from Persian Gulf. Pharmacognosy Magazine, 7(26), 97–100. https://doi.org/10.4103/0973-1296.80663