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    Evaluation of extracts of leaf of three Ficus deltoidea varieties for antioxidant activities and secondary metabolites

    Abdullah Zunoliza1★, Hussain Khalid1, Ismail Zhari1, Mat Ali Rasadah2, Pisar Mazura2, Jamaludin Fadzureena2, Sahdan Rohana2★ Corresponding author

    1. 1aSchool of Pharmaceutical Sciences, University Science of Malaysia, Minden Campus, 11800 Penang, Malaysia.
    2. 2bMedicinal Plants Division, Forest Research Institute Malaysia (FRIM), 52109 Kepong, Selangor, Malaysia.

    CORRESPONDENCE

    Abdullah Zunoliza

    Phone and fax +6046563443, ; zunoliza@frim.gov.my

    a_noliz@hotmail.com

    Received: 15-04-2009; Revised: 25-04-2009; Accepted: 02-06-2009.

    Volume 1, Issue 4 · pp. 216–223 · PUBLISHED Jul-Aug 2009 · DOI:

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Present study aimed to investigate alcoholic and aqueous extracts of three varieties of Ficus deltoidea for antioxidant activity using in vitro models such as free radical scavenging activity, reduction power of iron (III), superoxide anion (O -) scavenging, xanthine oxidase (XOD), nitric oxide (NO·) and lipid peroxidation. The total polyphenols, flavonoids and tannins were estimated using colorimetry in order to investigate their correlation with antioxidant activities. Alcoholic and aqueous extracts of different varieties of the plant exhibited different radical scavenging activities in different models (P<0.05). Both the types of extracts displayed high antioxidant activity in DPPH and superoxide anion scavenging models, and the activity was comparable to quercetin, rutin, butylated hydroxyanisole (BHA), ascorbic acid and allopurinol. A correlation was observed between antioxidant activity and content of total polyphenols, flavonoids and tannins. The results of this study indicate that the extracts of Ficus deltoidea possess promising antioxidant activity.

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      Zunoliza, A., Khalid, H., Zhari, I., Rasadah, M. A., Mazura, P., Fadzureena, J., & Rohana, S. (2009). Evaluation of extracts of leaf of three Ficus deltoidea varieties for antioxidant activities and secondary metabolites. Pharmacognosy Research, 1(4), 216–223.